1z25

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{{Seed}}
 
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[[Image:1z25.png|left|200px]]
 
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==Structure of P.furiosus Argonaute with bound Mn2+==
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The line below this paragraph, containing "STRUCTURE_1z25", creates the "Structure Box" on the page.
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<StructureSection load='1z25' size='340' side='right'caption='[[1z25]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1z25]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z25 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Z25 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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{{STRUCTURE_1z25| PDB=1z25 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1z25 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z25 OCA], [https://pdbe.org/1z25 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1z25 RCSB], [https://www.ebi.ac.uk/pdbsum/1z25 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1z25 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q8U3D2_PYRFU Q8U3D2_PYRFU]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z2/1z25_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1z25 ConSurf].
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<div style="clear:both"></div>
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===Structure of P.furiosus Argonaute with bound Mn2+===
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==See Also==
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*[[Argonaute 3D structures|Argonaute 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_15800637}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 15800637 is the PubMed ID number.
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{{ABSTRACT_PUBMED_15800637}}
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==About this Structure==
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1Z25 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z25 OCA].
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==Reference==
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Purified Argonaute2 and an siRNA form recombinant human RISC., Rivas FV, Tolia NH, Song JJ, Aragon JP, Liu J, Hannon GJ, Joshua-Tor L, Nat Struct Mol Biol. 2005 Apr;12(4):340-9. Epub 2005 Mar 30. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15800637 15800637]
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[[Category: Pyrococcus furiosus]]
[[Category: Pyrococcus furiosus]]
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[[Category: Single protein]]
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[[Category: Aragon JP]]
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[[Category: Aragon, J P.]]
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[[Category: Hannon GJ]]
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[[Category: Hannon, G J.]]
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[[Category: Joshua-Tor L]]
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[[Category: Joshua-Tor, L.]]
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[[Category: Liu J]]
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[[Category: Liu, J.]]
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[[Category: Rivas FV]]
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[[Category: Rivas, F V.]]
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[[Category: Song JJ]]
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[[Category: Song, J J.]]
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[[Category: Tolia NH]]
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[[Category: Tolia, N H.]]
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[[Category: Active site]]
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[[Category: Argonaute]]
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[[Category: Mg2+]]
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[[Category: Piwi]]
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[[Category: Rnai]]
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[[Category: Rnaseh]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 13:37:54 2008''
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Current revision

Structure of P.furiosus Argonaute with bound Mn2+

PDB ID 1z25

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