2cyc

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{{Seed}}
 
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[[Image:2cyc.png|left|200px]]
 
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==Crystal structure of Tyrosyl-tRNA Synthetase complexed with L-tyrosine from Pyrococcus horikoshii==
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The line below this paragraph, containing "STRUCTURE_2cyc", creates the "Structure Box" on the page.
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<StructureSection load='2cyc' size='340' side='right'caption='[[2cyc]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2cyc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii_OT3 Pyrococcus horikoshii OT3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CYC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CYC FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TYR:TYROSINE'>TYR</scene></td></tr>
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{{STRUCTURE_2cyc| PDB=2cyc | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cyc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cyc OCA], [https://pdbe.org/2cyc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cyc RCSB], [https://www.ebi.ac.uk/pdbsum/2cyc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cyc ProSAT], [https://www.topsan.org/Proteins/RSGI/2cyc TOPSAN]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SYY_PYRHO SYY_PYRHO] Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).[HAMAP-Rule:MF_02009]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cy/2cyc_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cyc ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of Tyrosyl-tRNA Synthetase complexed with L-tyrosine from Pyrococcus horikoshii===
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==See Also==
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*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
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__TOC__
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<!--
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_16325203}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 16325203 is the PubMed ID number.
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[[Category: Pyrococcus horikoshii OT3]]
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[[Category: Kobayashi T]]
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{{ABSTRACT_PUBMED_16325203}}
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[[Category: Kuratani M]]
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[[Category: Sakai H]]
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==About this Structure==
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[[Category: Sakamoto K]]
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2CYC is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CYC OCA].
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[[Category: Sekine S]]
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[[Category: Shirouzu M]]
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==Reference==
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[[Category: Takahashi M]]
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Crystal structures of tyrosyl-tRNA synthetases from Archaea., Kuratani M, Sakai H, Takahashi M, Yanagisawa T, Kobayashi T, Murayama K, Chen L, Liu ZJ, Wang BC, Kuroishi C, Kuramitsu S, Terada T, Bessho Y, Shirouzu M, Sekine S, Yokoyama S, J Mol Biol. 2006 Jan 20;355(3):395-408. Epub 2005 Nov 14. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16325203 16325203]
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[[Category: Terada T]]
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[[Category: Pyrococcus horikoshii]]
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[[Category: Yanagisawa T]]
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[[Category: Single protein]]
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[[Category: Yokoyama S]]
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[[Category: Tyrosine--tRNA ligase]]
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[[Category: Kobayashi, T.]]
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[[Category: Kuratani, M.]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Sakai, H.]]
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[[Category: Sakamoto, K.]]
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[[Category: Sekine, S.]]
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[[Category: Shirouzu, M.]]
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[[Category: Takahashi, M.]]
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[[Category: Terada, T.]]
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[[Category: Yanagisawa, T.]]
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[[Category: Yokoyama, S.]]
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[[Category: Aminoacylation]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: Riken structural genomics/proteomics initiative]]
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[[Category: Rsgi]]
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[[Category: Structural genomic]]
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[[Category: Tyrosine]]
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[[Category: Tyrr]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 13:46:11 2008''
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Current revision

Crystal structure of Tyrosyl-tRNA Synthetase complexed with L-tyrosine from Pyrococcus horikoshii

PDB ID 2cyc

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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