1z0b

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{{Seed}}
 
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[[Image:1z0b.png|left|200px]]
 
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==Crystal Structure of A. fulgidus Lon proteolytic domain E506A mutant==
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The line below this paragraph, containing "STRUCTURE_1z0b", creates the "Structure Box" on the page.
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<StructureSection load='1z0b' size='340' side='right'caption='[[1z0b]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1z0b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z0B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Z0B FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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{{STRUCTURE_1z0b| PDB=1z0b | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1z0b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z0b OCA], [https://pdbe.org/1z0b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1z0b RCSB], [https://www.ebi.ac.uk/pdbsum/1z0b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1z0b ProSAT]</span></td></tr>
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</table>
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===Crystal Structure of A. fulgidus Lon proteolytic domain E506A mutant===
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== Function ==
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[https://www.uniprot.org/uniprot/LONB_ARCFU LONB_ARCFU] ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Degrades polypeptides processively (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 16002085 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z0/1z0b_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_16002085}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1Z0B is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z0B OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1z0b ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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Atomic-resolution crystal structure of the proteolytic domain of Archaeoglobus fulgidus lon reveals the conformational variability in the active sites of lon proteases., Botos I, Melnikov EE, Cherry S, Kozlov S, Makhovskaya OV, Tropea JE, Gustchina A, Rotanova TV, Wlodawer A, J Mol Biol. 2005 Aug 5;351(1):144-57. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16002085 16002085]
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</StructureSection>
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Pathological crystallography: case studies of several unusual macromolecular crystals., Dauter Z, Botos I, LaRonde-LeBlanc N, Wlodawer A, Acta Crystallogr D Biol Crystallogr. 2005 Jul;61(Pt 7):967-75. Epub 2005, Jun 24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15983420 15983420]
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[[Category: Archaeoglobus fulgidus]]
[[Category: Archaeoglobus fulgidus]]
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[[Category: Endopeptidase La]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Botos I]]
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[[Category: Botos, I.]]
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[[Category: Cherry S]]
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[[Category: Cherry, S.]]
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[[Category: Gustchina A]]
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[[Category: Gustchina, A.]]
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[[Category: Kozlov S]]
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[[Category: Kozlov, S.]]
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[[Category: Makhovskaya OV]]
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[[Category: Makhovskaya, O V.]]
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[[Category: Melnikov EE]]
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[[Category: Melnikov, E E.]]
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[[Category: Rotanova TV]]
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[[Category: Rotanova, T V.]]
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[[Category: Tropea JE]]
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[[Category: Tropea, J E]]
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[[Category: Wlodawer A]]
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[[Category: Wlodawer, A.]]
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[[Category: Atp-dependent protease]]
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[[Category: B-type lon]]
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[[Category: Catalytic ser-lys dyad]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 13:57:12 2008''
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Current revision

Crystal Structure of A. fulgidus Lon proteolytic domain E506A mutant

PDB ID 1z0b

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