1obb

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{{Seed}}
 
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[[Image:1obb.png|left|200px]]
 
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==alpha-glucosidase A, AglA, from Thermotoga maritima in complex with maltose and NAD+==
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The line below this paragraph, containing "STRUCTURE_1obb", creates the "Structure Box" on the page.
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<StructureSection load='1obb' size='340' side='right'caption='[[1obb]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1obb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima_MSB8 Thermotoga maritima MSB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OBB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OBB FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=PRD_900001:alpha-maltose'>PRD_900001</scene></td></tr>
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{{STRUCTURE_1obb| PDB=1obb | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1obb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1obb OCA], [https://pdbe.org/1obb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1obb RCSB], [https://www.ebi.ac.uk/pdbsum/1obb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1obb ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/AGLA_THEMA AGLA_THEMA] alpha-glycosidase with a very broad specificity hydrolyzes maltose and other small maltooligosaccharides but is inactive against the polymeric substrate starch agla is not specific with respect to the configuration at the c-4 position of its substrates because glycosidic derivatives of d-galactose are also hydrolyzed does not cleave beta-glycosidic bonds
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ob/1obb_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1obb ConSurf].
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<div style="clear:both"></div>
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===ALPHA-GLUCOSIDASE A, AGLA, FROM THERMOTOGA MARITIMA IN COMPLEX WITH MALTOSE AND NAD+===
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==See Also==
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*[[Alpha-glucosidase 3D structures|Alpha-glucosidase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_12588867}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 12588867 is the PubMed ID number.
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[[Category: Thermotoga maritima MSB8]]
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[[Category: Hoffmann V]]
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{{ABSTRACT_PUBMED_12588867}}
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[[Category: Liebl W]]
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[[Category: Lodge JA]]
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==About this Structure==
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[[Category: Maier T]]
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1OBB is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OBB OCA].
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[[Category: Strater N]]
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==Reference==
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Crystal structure of Thermotoga maritima alpha-glucosidase AglA defines a new clan of NAD+-dependent glycosidases., Lodge JA, Maier T, Liebl W, Hoffmann V, Strater N, J Biol Chem. 2003 May 23;278(21):19151-8. Epub 2003 Feb 14. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12588867 12588867]
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[[Category: Alpha-glucosidase]]
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[[Category: Single protein]]
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[[Category: Thermotoga maritima]]
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[[Category: Hoffmann, V.]]
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[[Category: Liebl, W.]]
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[[Category: Lodge, J A.]]
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[[Category: Maier, T.]]
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[[Category: Strater, N.]]
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[[Category: Glycosidase]]
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[[Category: Hydrolase]]
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[[Category: Maltose]]
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[[Category: Nad+]]
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[[Category: Sulfinic acid]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 14:05:37 2008''
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Current revision

alpha-glucosidase A, AglA, from Thermotoga maritima in complex with maltose and NAD+

PDB ID 1obb

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