1xhe

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{{Seed}}
 
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[[Image:1xhe.png|left|200px]]
 
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==Crystal structure of the receiver domain of redox response regulator arca==
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The line below this paragraph, containing "STRUCTURE_1xhe", creates the "Structure Box" on the page.
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<StructureSection load='1xhe' size='340' side='right'caption='[[1xhe]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1xhe]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XHE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XHE FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xhe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xhe OCA], [https://pdbe.org/1xhe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xhe RCSB], [https://www.ebi.ac.uk/pdbsum/1xhe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xhe ProSAT]</span></td></tr>
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{{STRUCTURE_1xhe| PDB=1xhe | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ARCA_ECOLI ARCA_ECOLI] Member of the two-component regulatory system ArcB/ArcA. Represses a wide variety of aerobic enzymes under anaerobic conditions. Controls the resistance of E.coli to dyes; required for expression of the alkaline phosphatase and sex factor F genes; It also may be involved in the osmoregulation of envelope proteins. When activated by ArcB, it negatively regulates the expression of genes of aerobic function. Activates the transcription of the plfB operon by binding to its promoter.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xh/1xhe_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xhe ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of the receiver domain of redox response regulator arca===
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==See Also==
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*[[Response regulator 3D structure|Response regulator 3D structure]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_15876365}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 15876365 is the PubMed ID number.
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{{ABSTRACT_PUBMED_15876365}}
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==About this Structure==
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1XHE is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XHE OCA].
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==Reference==
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Structural analysis and solution studies of the activated regulatory domain of the response regulator ArcA: a symmetric dimer mediated by the alpha4-beta5-alpha5 face., Toro-Roman A, Mack TR, Stock AM, J Mol Biol. 2005 May 27;349(1):11-26. Epub 2005 Apr 7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15876365 15876365]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Mack, T R.]]
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[[Category: Mack TR]]
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[[Category: Stock, A M.]]
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[[Category: Stock AM]]
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[[Category: Toro-Roman, A.]]
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[[Category: Toro-Roman A]]
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[[Category: Anoxic redox control]]
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[[Category: Doubly wound five-stranded beta/alpha fold]]
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[[Category: Gene regulation]]
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[[Category: Transcription factor]]
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[[Category: Two-component system]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 14:14:08 2008''
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Current revision

Crystal structure of the receiver domain of redox response regulator arca

PDB ID 1xhe

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