2i9f

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{{Seed}}
 
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[[Image:2i9f.png|left|200px]]
 
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==Structure of the equine arterivirus nucleocapsid protein==
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The line below this paragraph, containing "STRUCTURE_2i9f", creates the "Structure Box" on the page.
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<StructureSection load='2i9f' size='340' side='right'caption='[[2i9f]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2i9f]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Equine_arteritis_virus Equine arteritis virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I9F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2I9F FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DTT:2,3-DIHYDROXY-1,4-DITHIOBUTANE'>DTT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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{{STRUCTURE_2i9f| PDB=2i9f | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2i9f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i9f OCA], [https://pdbe.org/2i9f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2i9f RCSB], [https://www.ebi.ac.uk/pdbsum/2i9f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2i9f ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/NCAP_EAVBU NCAP_EAVBU]
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Equine arteritis virus (EAV) is an enveloped positive-sense RNA virus belonging to the Arteriviridae family, which also includes the porcine pathogen PRRSV and is genetically and structurally related to the coronaviruses. EAV is an important equine pathogen that has caused significant economic losses to the horse-breeding industry and has been difficult to control. The EAV virion consists of a genome-containing nucleocapsid core made of nucleocapsid (N) protein surrounded by a lipid envelope containing several membrane proteins. Here, the crystal structure of the capsid-forming domain of the EAV N protein is presented at 2.0 A resolution. The dimeric N-protein structure is similar to the previously determined structure of the N protein from PRRSV, with most differences localized to the terminal helices and flexible loops. The N protein is organized as dimers of dimers in the crystal, which may reflect the arrangement of the protein in the viral nucleocapsid.
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===Structure of the equine arterivirus nucleocapsid protein===
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Structure of the equine arteritis virus nucleocapsid protein reveals a dimer-dimer arrangement.,Deshpande A, Wang S, Walsh MA, Dokland T Acta Crystallogr D Biol Crystallogr. 2007 May;63(Pt 5):581-6. Epub 2007, Apr 21. PMID:17452783<ref>PMID:17452783</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 2i9f" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 17452783 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_17452783}}
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__TOC__
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</StructureSection>
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==About this Structure==
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2I9F is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Equine_arteritis_virus Equine arteritis virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I9F OCA].
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==Reference==
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Structure of the equine arteritis virus nucleocapsid protein reveals a dimer-dimer arrangement., Deshpande A, Wang S, Walsh MA, Dokland T, Acta Crystallogr D Biol Crystallogr. 2007 May;63(Pt 5):581-6. Epub 2007, Apr 21. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17452783 17452783]
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[[Category: Equine arteritis virus]]
[[Category: Equine arteritis virus]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Deshpande, A.]]
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[[Category: Deshpande A]]
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[[Category: Dokland, T.]]
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[[Category: Dokland T]]
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[[Category: Walsh, M.]]
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[[Category: Walsh M]]
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[[Category: Wang, S.]]
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[[Category: Wang S]]
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[[Category: Assembly]]
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[[Category: Capsid]]
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[[Category: Crystallography]]
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[[Category: Structure]]
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[[Category: Virus]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 14:28:20 2008''
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Current revision

Structure of the equine arterivirus nucleocapsid protein

PDB ID 2i9f

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