1tyg

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{{Seed}}
 
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[[Image:1tyg.png|left|200px]]
 
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==Structure of the thiazole synthase/ThiS complex==
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The line below this paragraph, containing "STRUCTURE_1tyg", creates the "Structure Box" on the page.
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<StructureSection load='1tyg' size='340' side='right'caption='[[1tyg]], [[Resolution|resolution]] 3.15&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1tyg]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TYG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TYG FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.15&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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{{STRUCTURE_1tyg| PDB=1tyg | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tyg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tyg OCA], [https://pdbe.org/1tyg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tyg RCSB], [https://www.ebi.ac.uk/pdbsum/1tyg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tyg ProSAT]</span></td></tr>
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</table>
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===Structure of the thiazole synthase/ThiS complex===
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== Function ==
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[https://www.uniprot.org/uniprot/THIS_BACSU THIS_BACSU] Is the sulfur donor in the synthesis of the thiazole phosphate moiety of thiamine phosphate.<ref>PMID:15489164</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_15362849}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 15362849 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ty/1tyg_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_15362849}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1TYG is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TYG OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1tyg ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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Thiamin biosynthesis in Bacillus subtilis: structure of the thiazole synthase/sulfur carrier protein complex., Settembre EC, Dorrestein PC, Zhai H, Chatterjee A, McLafferty FW, Begley TP, Ealick SE, Biochemistry. 2004 Sep 21;43(37):11647-57. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15362849 15362849]
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<references/>
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__TOC__
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</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
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[[Category: Protein complex]]
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[[Category: Large Structures]]
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[[Category: Begley, T P.]]
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[[Category: Begley TP]]
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[[Category: Chatterjee, A.]]
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[[Category: Chatterjee A]]
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[[Category: Dorrestein, P C.]]
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[[Category: Dorrestein PC]]
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[[Category: Ealick, S E.]]
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[[Category: Ealick SE]]
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[[Category: McLafferty, F W.]]
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[[Category: McLafferty FW]]
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[[Category: Settembre, E C.]]
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[[Category: Settembre EC]]
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[[Category: Zhai, H.]]
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[[Category: Zhai H]]
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[[Category: Alpha beta barrel]]
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[[Category: Protein-protein complex]]
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[[Category: Thig]]
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[[Category: These]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 14:29:50 2008''
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Current revision

Structure of the thiazole synthase/ThiS complex

PDB ID 1tyg

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