1xva

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{{Seed}}
 
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[[Image:1xva.png|left|200px]]
 
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<!--
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==METHYLTRANSFERASE==
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The line below this paragraph, containing "STRUCTURE_1xva", creates the "Structure Box" on the page.
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<StructureSection load='1xva' size='340' side='right'caption='[[1xva]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1xva]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XVA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XVA FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr>
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{{STRUCTURE_1xva| PDB=1xva | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xva OCA], [https://pdbe.org/1xva PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xva RCSB], [https://www.ebi.ac.uk/pdbsum/1xva PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xva ProSAT]</span></td></tr>
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</table>
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===METHYLTRANSFERASE===
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== Function ==
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[https://www.uniprot.org/uniprot/GNMT_RAT GNMT_RAT] Catalyzes the methylation of glycine by using S-adenosylmethionine (AdoMet) to form N-methylglycine (sarcosine) with the concomitant production of S-adenosylhomocysteine (AdoHcy). Possible crucial role in the regulation of tissue concentration of AdoMet and of metabolism of methionine.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_8810903}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 8810903 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xv/1xva_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_8810903}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1XVA is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XVA OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xva ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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Crystal structure of glycine N-methyltransferase from rat liver., Fu Z, Hu Y, Konishi K, Takata Y, Ogawa H, Gomi T, Fujioka M, Takusagawa F, Biochemistry. 1996 Sep 17;35(37):11985-93. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8810903 8810903]
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Glycine N-methyltransferase]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Fu Z]]
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[[Category: Fu, Z.]]
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[[Category: Fujioka M]]
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[[Category: Fujioka, M.]]
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[[Category: Gomi T]]
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[[Category: Gomi, T.]]
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[[Category: Hu Y]]
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[[Category: Hu, Y.]]
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[[Category: Konishi K]]
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[[Category: Konishi, K.]]
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[[Category: Ogawa H]]
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[[Category: Ogawa, H.]]
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[[Category: Takata Y]]
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[[Category: Takata, Y.]]
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[[Category: Takusagawa F]]
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[[Category: Takusagawa, F.]]
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[[Category: Methyltransferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 15:08:43 2008''
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Current revision

METHYLTRANSFERASE

PDB ID 1xva

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