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2qim

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{{Seed}}
 
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[[Image:2qim.png|left|200px]]
 
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==Crystal Structure of Pathogenesis-related Protein LlPR-10.2B from yellow lupine in complex with Cytokinin==
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The line below this paragraph, containing "STRUCTURE_2qim", creates the "Structure Box" on the page.
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<StructureSection load='2qim' size='340' side='right'caption='[[2qim]], [[Resolution|resolution]] 1.35&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2qim]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lupinus_luteus Lupinus luteus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QIM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QIM FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.35&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZEA:(2E)-2-METHYL-4-(9H-PURIN-6-YLAMINO)BUT-2-EN-1-OL'>ZEA</scene></td></tr>
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{{STRUCTURE_2qim| PDB=2qim | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qim FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qim OCA], [https://pdbe.org/2qim PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qim RCSB], [https://www.ebi.ac.uk/pdbsum/2qim PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qim ProSAT]</span></td></tr>
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</table>
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===Crystal Structure of Pathogenesis-related Protein LlPR-10.2B from yellow lupine in complex with Cytokinin===
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== Function ==
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[https://www.uniprot.org/uniprot/P102B_LUPLU P102B_LUPLU] Class II ribonuclease (RNase) (By similarity). Binds to several cytokinins including natural adenine-type (e.g. trans-zeatin and kinetin) and artificial urea-type (e.g. N,N'-diphenylurea and N-phenyl-N'-(2-chloro-4-pyridyl)urea) hormones (PubMed:18406424, PubMed:19220853, PubMed:29630775). Interacts with melatonin (PubMed:29630775).[UniProtKB:P52779]<ref>PMID:18406424</ref> <ref>PMID:19220853</ref> <ref>PMID:29630775</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_18406424}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 18406424 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qi/2qim_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_18406424}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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2QIM is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Lupinus_luteus Lupinus luteus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QIM OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qim ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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Lupinus luteus pathogenesis-related protein as a reservoir for cytokinin., Fernandes H, Pasternak O, Bujacz G, Bujacz A, Sikorski MM, Jaskolski M, J Mol Biol. 2008 May 16;378(5):1040-51. Epub 2008 Mar 19. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18406424 18406424]
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<references/>
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__TOC__
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Structure of a yellow lupin pathogenesis-related PR-10 protein belonging to a novel subclass., Pasternak O, Biesiadka J, Dolot R, Handschuh L, Bujacz G, Sikorski MM, Jaskolski M, Acta Crystallogr D Biol Crystallogr. 2005 Jan;61(Pt 1):99-107. Epub 2004, Dec 17. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15608381 15608381]
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</StructureSection>
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[[Category: Large Structures]]
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Crystal structures of two homologous pathogenesis-related proteins from yellow lupine., Biesiadka J, Bujacz G, Sikorski MM, Jaskolski M, J Mol Biol. 2002 Jun 21;319(5):1223-34. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12079359 12079359]
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Crystal structure of Vigna radiata cytokinin-specific binding protein in complex with zeatin., Pasternak O, Bujacz GD, Fujimoto Y, Hashimoto Y, Jelen F, Otlewski J, Sikorski MM, Jaskolski M, Plant Cell. 2006 Oct;18(10):2622-34. Epub 2006 Sep 22. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16998071 16998071]
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X-ray and NMR structure of Bet v 1, the origin of birch pollen allergy., Gajhede M, Osmark P, Poulsen FM, Ipsen H, Larsen JN, Joost van Neerven RJ, Schou C, Lowenstein H, Spangfort MD, Nat Struct Biol. 1996 Dec;3(12):1040-5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8946858 8946858]
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Crystal structure of a hypoallergenic isoform of the major birch pollen allergen Bet v 1 and its likely biological function as a plant steroid carrier., Markovic-Housley Z, Degano M, Lamba D, von Roepenack-Lahaye E, Clemens S, Susani M, Ferreira F, Scheiner O, Breiteneder H, J Mol Biol. 2003 Jan 3;325(1):123-33. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12473456 12473456]
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[[Category: Lupinus luteus]]
[[Category: Lupinus luteus]]
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[[Category: Single protein]]
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[[Category: Bujacz A]]
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[[Category: Bujacz, A.]]
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[[Category: Bujacz G]]
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[[Category: Bujacz, G.]]
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[[Category: Fernandes HC]]
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[[Category: Fernandes, H C.]]
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[[Category: Jaskolski M]]
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[[Category: Jaskolski, M.]]
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[[Category: Pasternak O]]
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[[Category: Pasternak, O.]]
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[[Category: Sikorski MM]]
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[[Category: Sikorski, M M.]]
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[[Category: Allergen]]
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[[Category: Cytokinin]]
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[[Category: Pathogenesis-related protein]]
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[[Category: Plant hormone]]
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[[Category: Plant protein]]
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[[Category: Pr-10 protein]]
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[[Category: Trans-zeatin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 15:21:11 2008''
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Current revision

Crystal Structure of Pathogenesis-related Protein LlPR-10.2B from yellow lupine in complex with Cytokinin

PDB ID 2qim

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