2q13

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:13, 21 February 2024) (edit) (undo)
 
(9 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:2q13.png|left|200px]]
 
-
<!--
+
==Crystal structure of BAR-PH domain of APPL1==
-
The line below this paragraph, containing "STRUCTURE_2q13", creates the "Structure Box" on the page.
+
<StructureSection load='2q13' size='340' side='right'caption='[[2q13]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2q13]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q13 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Q13 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
-
-->
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2q13 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2q13 OCA], [https://pdbe.org/2q13 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2q13 RCSB], [https://www.ebi.ac.uk/pdbsum/2q13 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2q13 ProSAT]</span></td></tr>
-
{{STRUCTURE_2q13| PDB=2q13 | SCENE= }}
+
</table>
-
 
+
== Function ==
-
===Crystal structure of BAR-PH domain of APPL1===
+
[https://www.uniprot.org/uniprot/DP13A_HUMAN DP13A_HUMAN] Required for the regulation of cell proliferation in response to extracellular signals from an early endosomal compartment. Links Rab5 to nuclear signal transduction.<ref>PMID:10490823</ref> <ref>PMID:15016378</ref>
-
 
+
== Evolutionary Conservation ==
-
 
+
[[Image:Consurf_key_small.gif|200px|right]]
-
<!--
+
Check<jmol>
-
The line below this paragraph, {{ABSTRACT_PUBMED_17581628}}, adds the Publication Abstract to the page
+
<jmolCheckbox>
-
(as it appears on PubMed at http://www.pubmed.gov), where 17581628 is the PubMed ID number.
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/q1/2q13_consurf.spt"</scriptWhenChecked>
-
-->
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
{{ABSTRACT_PUBMED_17581628}}
+
<text>to colour the structure by Evolutionary Conservation</text>
-
 
+
</jmolCheckbox>
-
==About this Structure==
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2q13 ConSurf].
-
2Q13 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q13 OCA].
+
<div style="clear:both"></div>
-
 
+
== References ==
-
==Reference==
+
<references/>
-
Structure of the APPL1 BAR-PH domain and characterization of its interaction with Rab5., Zhu G, Chen J, Liu J, Brunzelle JS, Huang B, Wakeham N, Terzyan S, Li X, Rao Z, Li G, Zhang XC, EMBO J. 2007 Jul 25;26(14):3484-93. Epub 2007 Jun 21. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17581628 17581628]
+
__TOC__
 +
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Single protein]]
+
[[Category: Large Structures]]
-
[[Category: Zhang, X C.]]
+
[[Category: Zhang XC]]
-
[[Category: Zhu, G.]]
+
[[Category: Zhu G]]
-
[[Category: Appl1]]
+
-
[[Category: Bar domain]]
+
-
[[Category: Bar-ph domain]]
+
-
[[Category: Ph domain]]
+
-
[[Category: Protein transport]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 15:40:18 2008''
+

Current revision

Crystal structure of BAR-PH domain of APPL1

PDB ID 2q13

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2q13"
Personal tools