2fj2
From Proteopedia
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| - | {{Seed}} | ||
| - | [[Image:2fj2.png|left|200px]] | ||
| - | + | ==Crystal Structure of Viral Macrophage Inflammatory Protein-II== | |
| - | + | <StructureSection load='2fj2' size='340' side='right'caption='[[2fj2]], [[Resolution|resolution]] 2.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2fj2]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_herpesvirus_8_strain_GK18 Human herpesvirus 8 strain GK18]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FJ2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FJ2 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fj2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fj2 OCA], [https://pdbe.org/2fj2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fj2 RCSB], [https://www.ebi.ac.uk/pdbsum/2fj2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fj2 ProSAT]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | + | [https://www.uniprot.org/uniprot/VMI2_HHV8P VMI2_HHV8P] Blocks infection by several different human immunodeficiency virus type 1 (HIV-1) strains. This occurs because vMIP-II binds to a wide range of chemokine receptors. May form part of the response to host defenses contributing to virus-induced neoplasia and may have relevance to KSHV and HIV-I interactions. | |
| - | + | == Evolutionary Conservation == | |
| - | + | [[Image:Consurf_key_small.gif|200px|right]] | |
| - | == | + | Check<jmol> |
| - | + | <jmolCheckbox> | |
| - | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fj/2fj2_consurf.spt"</scriptWhenChecked> | |
| - | == | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> |
| - | + | <text>to colour the structure by Evolutionary Conservation</text> | |
| - | [ | + | </jmolCheckbox> |
| - | [[ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fj2 ConSurf]. |
| - | [ | + | <div style="clear:both"></div> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Human herpesvirus 8 strain GK18]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Cao R]] |
| - | [[Category: | + | [[Category: Dong CZ]] |
| - | [[Category: | + | [[Category: Gao YG]] |
| - | [[Category: | + | [[Category: Huang Z]] |
| - | [[Category: | + | [[Category: Kumar S]] |
| - | + | [[Category: Li Y]] | |
| - | + | [[Category: Liu D]] | |
| + | [[Category: Wilson SR]] | ||
Current revision
Crystal Structure of Viral Macrophage Inflammatory Protein-II
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Categories: Human herpesvirus 8 strain GK18 | Large Structures | Cao R | Dong CZ | Gao YG | Huang Z | Kumar S | Li Y | Liu D | Wilson SR
