1tjc

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{{Seed}}
 
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[[Image:1tjc.png|left|200px]]
 
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==Crystal structure of peptide-substrate-binding domain of human type I collagen prolyl 4-hydroxylase==
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The line below this paragraph, containing "STRUCTURE_1tjc", creates the "Structure Box" on the page.
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<StructureSection load='1tjc' size='340' side='right'caption='[[1tjc]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1tjc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TJC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TJC FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tjc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tjc OCA], [https://pdbe.org/1tjc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tjc RCSB], [https://www.ebi.ac.uk/pdbsum/1tjc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tjc ProSAT]</span></td></tr>
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{{STRUCTURE_1tjc| PDB=1tjc | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/P4HA1_HUMAN P4HA1_HUMAN] Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tj/1tjc_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1tjc ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of peptide-substrate-binding domain of human type I collagen prolyl 4-hydroxylase===
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==See Also==
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*[[Hydroxylases 3D structures|Hydroxylases 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_15456751}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 15456751 is the PubMed ID number.
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{{ABSTRACT_PUBMED_15456751}}
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==About this Structure==
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1TJC is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TJC OCA].
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==Reference==
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The peptide-substrate-binding domain of collagen prolyl 4-hydroxylases is a tetratricopeptide repeat domain with functional aromatic residues., Pekkala M, Hieta R, Bergmann U, Kivirikko KI, Wierenga RK, Myllyharju J, J Biol Chem. 2004 Dec 10;279(50):52255-61. Epub 2004 Sep 28. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15456751 15456751]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Procollagen-proline dioxygenase]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Bergmann U]]
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[[Category: Bergmann, U.]]
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[[Category: Hieta R]]
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[[Category: Hieta, R.]]
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[[Category: Kivirikko KI]]
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[[Category: Kivirikko, K I.]]
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[[Category: Myllyharju J]]
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[[Category: Myllyharju, J.]]
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[[Category: Pekkala M]]
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[[Category: Pekkala, M.]]
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[[Category: Wierenga RK]]
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[[Category: Wierenga, R K.]]
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[[Category: Helical bundle]]
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[[Category: Tpr]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 15:58:49 2008''
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Current revision

Crystal structure of peptide-substrate-binding domain of human type I collagen prolyl 4-hydroxylase

PDB ID 1tjc

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