1pqt

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{{Seed}}
 
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[[Image:1pqt.png|left|200px]]
 
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==REFINEMENT OF d(GCGAAGC) HAIRPIN STRUCTURE USING ONE- AND TWO-BOND RESIDUAL DIPOLAR COUPLINGS==
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The line below this paragraph, containing "STRUCTURE_1pqt", creates the "Structure Box" on the page.
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<StructureSection load='1pqt' size='340' side='right'caption='[[1pqt]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1pqt]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PQT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PQT FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1pqt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pqt OCA], [https://pdbe.org/1pqt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1pqt RCSB], [https://www.ebi.ac.uk/pdbsum/1pqt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pqt ProSAT]</span></td></tr>
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{{STRUCTURE_1pqt| PDB=1pqt | SCENE= }}
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</table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The structure of the 13C,15N-labeled d(GCGAAGC) hairpin, as determined by NMR spectroscopy and refined using molecular dynamics with NOE-derived distances, torsion angles, and residual dipolar couplings (RDCs), is presented. Although the studied molecule is of small size, it is demonstrated that the incorporation of diminutive RDCs can significantly improve local structure determination of regions undefined by the conventional restraints. Very good correlation between the experimental and back-calculated small one- and two-bond 1H-13C, 1H-15N, 13C-13C and 13C-15N coupling constants has been attained. The final structures clearly show typical features of the miniloop architecture. The structure is discussed in context of the extraordinary stability of the d(GCGAAGC) hairpin, which originates from a complex interplay between the aromatic base stacking and hydrogen bonding interactions.
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===REFINEMENT OF d(GCGAAGC) HAIRPIN STRUCTURE USING ONE- AND TWO-BOND RESIDUAL DIPOLAR COUPLINGS===
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Refinement of d(GCGAAGC) hairpin structure using one- and two-bond residual dipolar couplings.,Padrta P, Stefl R, Kralik L, Zidek L, Sklenar V J Biomol NMR. 2002 Sep;24(1):1-14. PMID:12449414<ref>PMID:12449414</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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The line below this paragraph, {{ABSTRACT_PUBMED_12449414}}, adds the Publication Abstract to the page
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<div class="pdbe-citations 1pqt" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 12449414 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_12449414}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Large Structures]]
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Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PQT OCA].
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[[Category: Padrta P]]
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[[Category: Sklenar V]]
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==Reference==
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[[Category: Stefl R]]
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Refinement of d(GCGAAGC) hairpin structure using one- and two-bond residual dipolar couplings., Padrta P, Stefl R, Kralik L, Zidek L, Sklenar V, J Biomol NMR. 2002 Sep;24(1):1-14. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12449414 12449414]
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[[Category: Zidek L]]
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[[Category: Padrta, P.]]
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[[Category: Sklenar, V.]]
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[[Category: Stefl, R.]]
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[[Category: Zidek, L.]]
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[[Category: Dna]]
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[[Category: Ga mismatch]]
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[[Category: Hairpin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 15:59:55 2008''
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Current revision

REFINEMENT OF d(GCGAAGC) HAIRPIN STRUCTURE USING ONE- AND TWO-BOND RESIDUAL DIPOLAR COUPLINGS

PDB ID 1pqt

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