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1sjj

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{{Seed}}
 
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[[Image:1sjj.png|left|200px]]
 
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==Cryo-EM Structure of Chicken Gizzard Smooth Muscle alpha-Actinin==
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The line below this paragraph, containing "STRUCTURE_1sjj", creates the "Structure Box" on the page.
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<StructureSection load='1sjj' size='340' side='right'caption='[[1sjj]], [[Resolution|resolution]] 20.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1sjj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SJJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SJJ FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron crystallography, [[Resolution|Resolution]] 20&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sjj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sjj OCA], [https://pdbe.org/1sjj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sjj RCSB], [https://www.ebi.ac.uk/pdbsum/1sjj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sjj ProSAT]</span></td></tr>
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{{STRUCTURE_1sjj| PDB=1sjj | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ACTN1_CHICK ACTN1_CHICK] F-actin cross-linking protein is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sj/1sjj_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1sjj ConSurf].
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<div style="clear:both"></div>
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===Cryo-EM Structure of Chicken Gizzard Smooth Muscle alpha-Actinin===
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==See Also==
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*[[Actinin 3D structures|Actinin 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_15050827}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 15050827 is the PubMed ID number.
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{{ABSTRACT_PUBMED_15050827}}
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==About this Structure==
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1SJJ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SJJ OCA].
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==Reference==
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A 3-D reconstruction of smooth muscle alpha-actinin by CryoEm reveals two different conformations at the actin-binding region., Liu J, Taylor DW, Taylor KA, J Mol Biol. 2004 Apr 16;338(1):115-25. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15050827 15050827]
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Projection image of smooth muscle alpha-actinin from two-dimensional crystals formed on positively charged lipid layers., Taylor KA, Taylor DW, J Mol Biol. 1993 Mar 5;230(1):196-205. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8450536 8450536]
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The three-dimensional structure of alpha-actinin obtained by cryoelectron microscopy suggests a model for Ca(2+)-dependent actin binding., Tang J, Taylor DW, Taylor KA, J Mol Biol. 2001 Jul 20;310(4):845-58. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11453692 11453692]
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Isoforms of alpha-actinin from cardiac, smooth, and skeletal muscle form polar arrays of actin filaments., Taylor KA, Taylor DW, Schachat F, J Cell Biol. 2000 May 1;149(3):635-46. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10791977 10791977]
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[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Liu, J.]]
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[[Category: Liu J]]
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[[Category: Taylor, D W.]]
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[[Category: Taylor DW]]
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[[Category: Taylor, K A.]]
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[[Category: Taylor KA]]
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[[Category: 3-helix bundle]]
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[[Category: Actin binding protein]]
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[[Category: Calmodulin-like domain]]
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[[Category: Calponin homology domain]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 16:10:06 2008''
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Current revision

Cryo-EM Structure of Chicken Gizzard Smooth Muscle alpha-Actinin

PDB ID 1sjj

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