1ri3

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{{Seed}}
 
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[[Image:1ri3.png|left|200px]]
 
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==Structure and mechanism of mRNA cap (guanine N-7) methyltransferase==
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The line below this paragraph, containing "STRUCTURE_1ri3", creates the "Structure Box" on the page.
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<StructureSection load='1ri3' size='340' side='right'caption='[[1ri3]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1ri3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Encephalitozoon_cuniculi Encephalitozoon cuniculi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RI3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RI3 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
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{{STRUCTURE_1ri3| PDB=1ri3 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ri3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ri3 OCA], [https://pdbe.org/1ri3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ri3 RCSB], [https://www.ebi.ac.uk/pdbsum/1ri3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ri3 ProSAT]</span></td></tr>
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</table>
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===Structure and mechanism of mRNA cap (guanine N-7) methyltransferase===
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== Function ==
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[https://www.uniprot.org/uniprot/MCES_ENCCU MCES_ENCCU] mRNA-capping methyltransferase that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs. Binds RNA containing 5'-terminal GpppC.<ref>PMID:15760890</ref>
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== Evolutionary Conservation ==
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 14731396 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ri/1ri3_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_14731396}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1RI3 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Encephalitozoon_cuniculi Encephalitozoon cuniculi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RI3 OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ri3 ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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Structure and mechanism of mRNA cap (guanine-N7) methyltransferase., Fabrega C, Hausmann S, Shen V, Shuman S, Lima CD, Mol Cell. 2004 Jan 16;13(1):77-89. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14731396 14731396]
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<references/>
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__TOC__
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</StructureSection>
[[Category: Encephalitozoon cuniculi]]
[[Category: Encephalitozoon cuniculi]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Fabrega, C.]]
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[[Category: Fabrega C]]
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[[Category: Hausmann, S.]]
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[[Category: Hausmann S]]
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[[Category: Lima, C D.]]
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[[Category: Lima CD]]
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[[Category: Shen, V.]]
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[[Category: Shen V]]
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[[Category: Shuman, S.]]
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[[Category: Shuman S]]
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[[Category: Cap]]
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[[Category: M7g]]
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[[Category: Messenger rna cap]]
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[[Category: Methyltransferase]]
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[[Category: Rna]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 16:45:57 2008''
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Current revision

Structure and mechanism of mRNA cap (guanine N-7) methyltransferase

PDB ID 1ri3

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