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1yyp
From Proteopedia
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| - | {{Seed}} | ||
| - | [[Image:1yyp.png|left|200px]] | ||
| - | + | ==Crystal structure of cytomegalovirus UL44 bound to C-terminal peptide from CMV UL54== | |
| - | + | <StructureSection load='1yyp' size='340' side='right'caption='[[1yyp]], [[Resolution|resolution]] 2.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1yyp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_betaherpesvirus_5 Human betaherpesvirus 5] and [https://en.wikipedia.org/wiki/Human_herpesvirus_5_strain_AD169 Human herpesvirus 5 strain AD169]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YYP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YYP FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yyp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yyp OCA], [https://pdbe.org/1yyp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yyp RCSB], [https://www.ebi.ac.uk/pdbsum/1yyp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yyp ProSAT]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | + | [https://www.uniprot.org/uniprot/VPAP_HCMVA VPAP_HCMVA] Accessory subunit of the DNA polymerase that acts to increase the processivity of polymerization.<ref>PMID:20538862</ref> | |
| - | + | == Evolutionary Conservation == | |
| - | < | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | + | Check<jmol> | |
| - | + | <jmolCheckbox> | |
| - | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yy/1yyp_consurf.spt"</scriptWhenChecked> | |
| - | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |
| - | + | <text>to colour the structure by Evolutionary Conservation</text> | |
| - | == | + | </jmolCheckbox> |
| - | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1yyp ConSurf]. | |
| - | + | <div style="clear:both"></div> | |
| - | == | + | == References == |
| - | + | <references/> | |
| - | [[Category: | + | __TOC__ |
| - | [[Category: Human herpesvirus 5]] | + | </StructureSection> |
| - | [[Category: | + | [[Category: Human betaherpesvirus 5]] |
| - | [[Category: Appleton | + | [[Category: Human herpesvirus 5 strain AD169]] |
| - | [[Category: Brooks | + | [[Category: Large Structures]] |
| - | [[Category: Coen | + | [[Category: Appleton BA]] |
| - | [[Category: Filman | + | [[Category: Brooks J]] |
| - | [[Category: Hogle | + | [[Category: Coen DM]] |
| - | [[Category: Loregian | + | [[Category: Filman DJ]] |
| - | + | [[Category: Hogle JM]] | |
| - | + | [[Category: Loregian A]] | |
| - | + | ||
Current revision
Crystal structure of cytomegalovirus UL44 bound to C-terminal peptide from CMV UL54
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