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1yyp

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{{Seed}}
 
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[[Image:1yyp.png|left|200px]]
 
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<!--
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==Crystal structure of cytomegalovirus UL44 bound to C-terminal peptide from CMV UL54==
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The line below this paragraph, containing "STRUCTURE_1yyp", creates the "Structure Box" on the page.
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<StructureSection load='1yyp' size='340' side='right'caption='[[1yyp]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1yyp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_betaherpesvirus_5 Human betaherpesvirus 5] and [https://en.wikipedia.org/wiki/Human_herpesvirus_5_strain_AD169 Human herpesvirus 5 strain AD169]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YYP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YYP FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_1yyp| PDB=1yyp | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yyp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yyp OCA], [https://pdbe.org/1yyp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yyp RCSB], [https://www.ebi.ac.uk/pdbsum/1yyp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yyp ProSAT]</span></td></tr>
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</table>
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===Crystal structure of cytomegalovirus UL44 bound to C-terminal peptide from CMV UL54===
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== Function ==
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[https://www.uniprot.org/uniprot/VPAP_HCMVA VPAP_HCMVA] Accessory subunit of the DNA polymerase that acts to increase the processivity of polymerization.<ref>PMID:20538862</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_16371349}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 16371349 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yy/1yyp_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_16371349}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1YYP is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Human_herpesvirus_5 Human herpesvirus 5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YYP OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1yyp ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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Crystal structure of the cytomegalovirus DNA polymerase subunit UL44 in complex with the C terminus from the catalytic subunit. Differences in structure and function relative to unliganded UL44., Appleton BA, Brooks J, Loregian A, Filman DJ, Coen DM, Hogle JM, J Biol Chem. 2006 Feb 24;281(8):5224-32. Epub 2005 Dec 20. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16371349 16371349]
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<references/>
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[[Category: DNA-directed DNA polymerase]]
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__TOC__
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[[Category: Human herpesvirus 5]]
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</StructureSection>
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[[Category: Protein complex]]
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[[Category: Human betaherpesvirus 5]]
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[[Category: Appleton, B A.]]
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[[Category: Human herpesvirus 5 strain AD169]]
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[[Category: Brooks, J.]]
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[[Category: Large Structures]]
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[[Category: Coen, D M.]]
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[[Category: Appleton BA]]
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[[Category: Filman, D J.]]
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[[Category: Brooks J]]
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[[Category: Hogle, J M.]]
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[[Category: Coen DM]]
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[[Category: Loregian, A]]
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[[Category: Filman DJ]]
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[[Category: Pcna]]
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[[Category: Hogle JM]]
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[[Category: Loregian A]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 17:08:29 2008''
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Current revision

Crystal structure of cytomegalovirus UL44 bound to C-terminal peptide from CMV UL54

PDB ID 1yyp

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