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1rgs

From Proteopedia

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{{Seed}}
 
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[[Image:1rgs.png|left|200px]]
 
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==REGULATORY SUBUNIT OF CAMP DEPENDENT PROTEIN KINASE==
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The line below this paragraph, containing "STRUCTURE_1rgs", creates the "Structure Box" on the page.
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<StructureSection load='1rgs' size='340' side='right'caption='[[1rgs]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1rgs]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. The August 2012 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''cAMP-dependent Protein Kinase (PKA)'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2012_8 10.2210/rcsb_pdb/mom_2012_8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RGS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RGS FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CMP:ADENOSINE-3,5-CYCLIC-MONOPHOSPHATE'>CMP</scene></td></tr>
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{{STRUCTURE_1rgs| PDB=1rgs | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1rgs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rgs OCA], [https://pdbe.org/1rgs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1rgs RCSB], [https://www.ebi.ac.uk/pdbsum/1rgs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1rgs ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/KAP0_BOVIN KAP0_BOVIN] Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rg/1rgs_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1rgs ConSurf].
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<div style="clear:both"></div>
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===REGULATORY SUBUNIT OF CAMP DEPENDENT PROTEIN KINASE===
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==See Also==
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*[[CAMP-dependent protein kinase 3D structures|CAMP-dependent protein kinase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_7638597}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 7638597 is the PubMed ID number.
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{{ABSTRACT_PUBMED_7638597}}
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==About this Structure==
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1RGS is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RGS OCA].
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==Reference==
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Regulatory subunit of protein kinase A: structure of deletion mutant with cAMP binding domains., Su Y, Dostmann WR, Herberg FW, Durick K, Xuong NH, Ten Eyck L, Taylor SS, Varughese KI, Science. 1995 Aug 11;269(5225):807-13. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7638597 7638597]
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[[Category: Bos taurus]]
[[Category: Bos taurus]]
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[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: RCSB PDB Molecule of the Month]]
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[[Category: Dostmann, W R.G.]]
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[[Category: Dostmann WRG]]
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[[Category: Durick, K.]]
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[[Category: Durick K]]
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[[Category: Eyck, L Ten.]]
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[[Category: Herberg FW]]
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[[Category: Herberg, F W.]]
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[[Category: Su Y]]
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[[Category: Su, Y.]]
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[[Category: Taylor SS]]
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[[Category: Taylor, S S.]]
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[[Category: Ten Eyck L]]
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[[Category: Varughese, K I.]]
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[[Category: Varughese KI]]
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[[Category: Xuong, N H.]]
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[[Category: Xuong N-H]]
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[[Category: Kinase]]
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[[Category: Regulatory subunit]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 17:13:28 2008''
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Current revision

REGULATORY SUBUNIT OF CAMP DEPENDENT PROTEIN KINASE

PDB ID 1rgs

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