1qqn

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:16, 14 February 2024) (edit) (undo)
 
(12 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1qqn.png|left|200px]]
 
-
<!--
+
==D206S MUTANT OF BOVINE 70 KILODALTON HEAT SHOCK PROTEIN==
-
The line below this paragraph, containing "STRUCTURE_1qqn", creates the "Structure Box" on the page.
+
<StructureSection load='1qqn' size='340' side='right'caption='[[1qqn]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1qqn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QQN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QQN FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-
{{STRUCTURE_1qqn| PDB=1qqn | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qqn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qqn OCA], [https://pdbe.org/1qqn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qqn RCSB], [https://www.ebi.ac.uk/pdbsum/1qqn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qqn ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/HSP7C_BOVIN HSP7C_BOVIN] Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex (By similarity).
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qq/1qqn_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qqn ConSurf].
 +
<div style="clear:both"></div>
-
===D206S MUTANT OF BOVINE 70 KILODALTON HEAT SHOCK PROTEIN===
+
==See Also==
-
 
+
*[[Heat Shock Protein structures|Heat Shock Protein structures]]
-
 
+
__TOC__
-
<!--
+
</StructureSection>
-
The line below this paragraph, {{ABSTRACT_PUBMED_10451379}}, adds the Publication Abstract to the page
+
-
(as it appears on PubMed at http://www.pubmed.gov), where 10451379 is the PubMed ID number.
+
-
-->
+
-
{{ABSTRACT_PUBMED_10451379}}
+
-
 
+
-
==About this Structure==
+
-
1QQN is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QQN OCA].
+
-
 
+
-
==Reference==
+
-
Mapping the role of active site residues for transducing an ATP-induced conformational change in the bovine 70-kDa heat shock cognate protein., Johnson ER, McKay DB, Biochemistry. 1999 Aug 17;38(33):10823-30. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10451379 10451379]
+
[[Category: Bos taurus]]
[[Category: Bos taurus]]
-
[[Category: Single protein]]
+
[[Category: Large Structures]]
-
[[Category: Johnson, E R.]]
+
[[Category: Johnson ER]]
-
[[Category: McKay, D B.]]
+
[[Category: McKay DB]]
-
[[Category: Atpase]]
+
-
[[Category: Molecular chaperone]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 17:17:56 2008''
+

Current revision

D206S MUTANT OF BOVINE 70 KILODALTON HEAT SHOCK PROTEIN

PDB ID 1qqn

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1qqn"
Personal tools