1noh

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:23, 16 August 2023) (edit) (undo)
 
(8 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1noh.png|left|200px]]
 
-
<!--
+
==The structure of bacteriophage phi29 scaffolding protein gp7 after prohead assembly==
-
The line below this paragraph, containing "STRUCTURE_1noh", creates the "Structure Box" on the page.
+
<StructureSection load='1noh' size='340' side='right'caption='[[1noh]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1noh]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_virus_phi29 Bacillus virus phi29]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NOH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NOH FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
-
-->
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1noh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1noh OCA], [https://pdbe.org/1noh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1noh RCSB], [https://www.ebi.ac.uk/pdbsum/1noh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1noh ProSAT]</span></td></tr>
-
{{STRUCTURE_1noh| PDB=1noh | SCENE= }}
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/SCAF_BPPH2 SCAF_BPPH2] Scaffolding protein involved in the icosahedric procapsid assembly. Coassembles with the capsid proteins to form the procapsid, in which the scaffolding protein is found within the external shell of icosahedrally arranged capsid protein subunits. In a subsequent step the scaffolding protein molecules are released from the procapsid.<ref>PMID:17098197</ref> <ref>PMID:17198713</ref> <ref>PMID:23896641</ref>
 +
<div style="background-color:#fffaf0;">
 +
== Publication Abstract from PubMed ==
 +
Three-dimensional structures of the double-stranded DNA bacteriophage phi29 scaffolding protein (gp7) before and after prohead assembly have been determined at resolutions of 2.2 and 2.8 A, respectively. Both structures are dimers that resemble arrows, with a four-helix bundle composing the arrowhead and a coiled coil forming the tail. The structural resemblance of gp7 to the yeast transcription factor GCN4 suggests a DNA-binding function that was confirmed by native gel electrophoresis. DNA binding to gp7 may have a role in mediating the structural transition from prohead to mature virus and scaffold release. A cryo-EM analysis indicates that gp7 is arranged inside the capsid as a series of concentric shells. The position of the higher density features in these shells correlates with the positions of hexamers in the equatorial region of the capsid, suggesting that gp7 may regulate formation of the prolate head through interactions with these hexamers.
-
===The structure of bacteriophage phi29 scaffolding protein gp7 after prohead assembly===
+
Bacteriophage phi29 scaffolding protein gp7 before and after prohead assembly.,Morais MC, Kanamaru S, Badasso MO, Koti JS, Owen BA, McMurray CT, Anderson DL, Rossmann MG Nat Struct Biol. 2003 Jul;10(7):572-6. PMID:12778115<ref>PMID:12778115</ref>
-
 
+
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-
<!--
+
</div>
-
The line below this paragraph, {{ABSTRACT_PUBMED_12778115}}, adds the Publication Abstract to the page
+
<div class="pdbe-citations 1noh" style="background-color:#fffaf0;"></div>
-
(as it appears on PubMed at http://www.pubmed.gov), where 12778115 is the PubMed ID number.
+
== References ==
-
-->
+
<references/>
-
{{ABSTRACT_PUBMED_12778115}}
+
__TOC__
-
 
+
</StructureSection>
-
==About this Structure==
+
[[Category: Bacillus virus phi29]]
-
1NOH is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_phage_phi29 Bacillus phage phi29]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NOH OCA].
+
[[Category: Large Structures]]
-
 
+
[[Category: Badasso MO]]
-
==Reference==
+
[[Category: Kanamaru S]]
-
Bacteriophage phi29 scaffolding protein gp7 before and after prohead assembly., Morais MC, Kanamaru S, Badasso MO, Koti JS, Owen BA, McMurray CT, Anderson DL, Rossmann MG, Nat Struct Biol. 2003 Jul;10(7):572-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12778115 12778115]
+
[[Category: Koti JS]]
-
[[Category: Bacillus phage phi29]]
+
[[Category: L Anderson D]]
-
[[Category: Single protein]]
+
[[Category: McMurray CT]]
-
[[Category: Anderson, D L.]]
+
[[Category: Morais MC]]
-
[[Category: Badasso, M O.]]
+
[[Category: Owen BL]]
-
[[Category: Kanamaru, S.]]
+
[[Category: Rossmann MG]]
-
[[Category: Koti, J S.]]
+
-
[[Category: McMurray, C T.]]
+
-
[[Category: Morais, M C.]]
+
-
[[Category: Owen, B L.]]
+
-
[[Category: Rossmann, M G.]]
+
-
[[Category: Coiled-coil]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 17:58:03 2008''
+

Current revision

The structure of bacteriophage phi29 scaffolding protein gp7 after prohead assembly

PDB ID 1noh

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1noh"
Personal tools