2jel

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{{Seed}}
 
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[[Image:2jel.png|left|200px]]
 
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==JEL42 FAB/HPR COMPLEX==
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The line below this paragraph, containing "STRUCTURE_2jel", creates the "Structure Box" on the page.
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<StructureSection load='2jel' size='340' side='right'caption='[[2jel]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2jel]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1jel 1jel]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JEL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JEL FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_2jel| PDB=2jel | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jel FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jel OCA], [https://pdbe.org/2jel PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jel RCSB], [https://www.ebi.ac.uk/pdbsum/2jel PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jel ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PTHP_ECOLI PTHP_ECOLI] General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the permease (enzymes II/III).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/je/2jel_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jel ConSurf].
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<div style="clear:both"></div>
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===JEL42 FAB/HPR COMPLEX===
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==See Also==
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*[[Antibody 3D structures|Antibody 3D structures]]
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*[[Phosphocarrier protein HPr 3D structures|Phosphocarrier protein HPr 3D structures]]
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*[[3D structures of non-human antibody|3D structures of non-human antibody]]
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 9671553 is the PubMed ID number.
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</StructureSection>
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{{ABSTRACT_PUBMED_9671553}}
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==About this Structure==
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2JEL is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1jel 1jel]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JEL OCA].
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==Reference==
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The 2.5 A resolution structure of the jel42 Fab fragment/HPr complex., Prasad L, Waygood EB, Lee JS, Delbaere LT, J Mol Biol. 1998 Jul 31;280(5):829-45. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9671553 9671553]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Single protein]]
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[[Category: Delbaere LTJ]]
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[[Category: Delbaere, L T.J.]]
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[[Category: Lee JS]]
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[[Category: Lee, J S.]]
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[[Category: Prasad L]]
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[[Category: Prasad, L.]]
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[[Category: Waygood EB]]
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[[Category: Waygood, E B.]]
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[[Category: Antibody-protein complex]]
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[[Category: Histidine-containing protein]]
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[[Category: Molecular recognition]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 18:05:39 2008''
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Current revision

JEL42 FAB/HPR COMPLEX

PDB ID 2jel

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