1qyd

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{{Seed}}
 
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[[Image:1qyd.png|left|200px]]
 
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==Crystal structures of pinoresinol-lariciresinol and phenylcoumaran benzylic ether reductases, and their relationship to isoflavone reductases==
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The line below this paragraph, containing "STRUCTURE_1qyd", creates the "Structure Box" on the page.
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<StructureSection load='1qyd' size='340' side='right'caption='[[1qyd]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1qyd]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thuja_plicata Thuja plicata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QYD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QYD FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qyd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qyd OCA], [https://pdbe.org/1qyd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qyd RCSB], [https://www.ebi.ac.uk/pdbsum/1qyd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qyd ProSAT]</span></td></tr>
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{{STRUCTURE_1qyd| PDB=1qyd | SCENE= }}
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</table>
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== Function ==
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===Crystal structures of pinoresinol-lariciresinol and phenylcoumaran benzylic ether reductases, and their relationship to isoflavone reductases===
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[https://www.uniprot.org/uniprot/PILR1_THUPL PILR1_THUPL] Reductase involved in lignan biosynthesis. Catalyzes the enantioselective sequential conversion of (-)-pinoresinol into (-)-lariciresinol and of (-)-lariciresinol into (+)-secoisolariciresinol. Can also convert with a lower efficiency (+)-pinoresinol into (+)-lariciresinol, but not (+)-lariciresinol into (-)-secoisolariciresinol. Abstracts the 4R-hydride from the NADPH cofactor during catalysis.<ref>PMID:9872995</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 13129921 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qy/1qyd_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_13129921}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qyd ConSurf].
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1QYD is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thuja_plicata Thuja plicata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QYD OCA].
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<div style="clear:both"></div>
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== References ==
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==Reference==
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<references/>
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Crystal structures of pinoresinol-lariciresinol and phenylcoumaran benzylic ether reductases and their relationship to isoflavone reductases., Min T, Kasahara H, Bedgar DL, Youn B, Lawrence PK, Gang DR, Halls SC, Park H, Hilsenbeck JL, Davin LB, Lewis NG, Kang C, J Biol Chem. 2003 Dec 12;278(50):50714-23. Epub 2003 Sep 16. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/13129921 13129921]
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__TOC__
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[[Category: Single protein]]
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Thuja plicata]]
[[Category: Thuja plicata]]
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[[Category: Bedgar, D L.]]
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[[Category: Bedgar DL]]
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[[Category: Davin, L B.]]
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[[Category: Davin LB]]
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[[Category: Gang, D R.]]
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[[Category: Gang DR]]
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[[Category: Halls, S C.]]
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[[Category: Halls SC]]
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[[Category: Hilsenbeck, J L.]]
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[[Category: Hilsenbeck JL]]
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[[Category: Kang, C.]]
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[[Category: Kang C]]
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[[Category: Kasahara, H.]]
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[[Category: Kasahara H]]
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[[Category: Lawrence, P K.]]
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[[Category: Lawrence PK]]
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[[Category: Min, T.]]
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[[Category: Min T]]
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[[Category: Park, H.]]
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[[Category: Park H]]
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[[Category: Youn, B.]]
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[[Category: Youn B]]
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[[Category: Ifr]]
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[[Category: Isoflavonoid]]
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[[Category: Lignan]]
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[[Category: Nadph-dependent aromatic alcohol reductase]]
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[[Category: Pcber]]
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[[Category: Plr]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 18:22:31 2008''
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Current revision

Crystal structures of pinoresinol-lariciresinol and phenylcoumaran benzylic ether reductases, and their relationship to isoflavone reductases

PDB ID 1qyd

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