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1s0u

From Proteopedia

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{{Seed}}
 
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[[Image:1s0u.png|left|200px]]
 
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<!--
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==eIF2gamma apo==
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The line below this paragraph, containing "STRUCTURE_1s0u", creates the "Structure Box" on the page.
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<StructureSection load='1s0u' size='340' side='right'caption='[[1s0u]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1s0u]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S0U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1S0U FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_1s0u| PDB=1s0u | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1s0u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s0u OCA], [https://pdbe.org/1s0u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1s0u RCSB], [https://www.ebi.ac.uk/pdbsum/1s0u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1s0u ProSAT]</span></td></tr>
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</table>
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===eIF2gamma apo===
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== Function ==
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[https://www.uniprot.org/uniprot/IF2G_METJA IF2G_METJA] eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA (By similarity).
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== Evolutionary Conservation ==
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<!--
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_14688270}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 14688270 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/s0/1s0u_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_14688270}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1S0U is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S0U OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1s0u ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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X-ray structure of translation initiation factor eIF2gamma: implications for tRNA and eIF2alpha binding., Roll-Mecak A, Alone P, Cao C, Dever TE, Burley SK, J Biol Chem. 2004 Mar 12;279(11):10634-42. Epub 2003 Dec 19. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14688270 14688270]
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Methanocaldococcus jannaschii]]
[[Category: Methanocaldococcus jannaschii]]
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[[Category: Single protein]]
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[[Category: Alone P]]
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[[Category: Alone, P.]]
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[[Category: Burley SK]]
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[[Category: Burley, S K.]]
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[[Category: Cao C]]
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[[Category: Cao, C.]]
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[[Category: Dever TE]]
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[[Category: Dever, T E.]]
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[[Category: Roll-Mecak A]]
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[[Category: Roll-Mecak, A.]]
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[[Category: Ef-1a]]
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[[Category: Eif2]]
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[[Category: Gtpase]]
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[[Category: Translation initiation]]
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[[Category: Trna]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 18:43:34 2008''
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Current revision

eIF2gamma apo

PDB ID 1s0u

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