1knw
From Proteopedia
(Difference between revisions)
(New page: 200px<br /><applet load="1knw" size="450" color="white" frame="true" align="right" spinBox="true" caption="1knw, resolution 2.10Å" /> '''Crystal structure of...) |
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| - | [[Image:1knw.gif|left|200px]]<br /><applet load="1knw" size="450" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="1knw, resolution 2.10Å" /> | ||
| - | '''Crystal structure of diaminopimelate decarboxylase'''<br /> | ||
| - | == | + | ==Crystal structure of diaminopimelate decarboxylase== |
| - | + | <StructureSection load='1knw' size='340' side='right'caption='[[1knw]], [[Resolution|resolution]] 2.10Å' scene=''> | |
| - | + | == Structural highlights == | |
| + | <table><tr><td colspan='2'>[[1knw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KNW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KNW FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LI:LITHIUM+ION'>LI</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1knw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1knw OCA], [https://pdbe.org/1knw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1knw RCSB], [https://www.ebi.ac.uk/pdbsum/1knw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1knw ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/DCDA_ECOLI DCDA_ECOLI] Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine. Is not active against the DD- or LL-isomers of diaminopimelate.<ref>PMID:14343156</ref> <ref>PMID:11856852</ref> <ref>PMID:18508763</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kn/1knw_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1knw ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Blagova | + | [[Category: Blagova L]] |
| - | [[Category: Bose | + | [[Category: Bose N]] |
| - | [[Category: Levdikov | + | [[Category: Levdikov V]] |
| - | [[Category: Momany | + | [[Category: Momany C]] |
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Current revision
Crystal structure of diaminopimelate decarboxylase
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