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2rds

From Proteopedia

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{{Seed}}
 
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[[Image:2rds.png|left|200px]]
 
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==Crystal Structure of PtlH with Fe/oxalylglycine and ent-1-deoxypentalenic acid bound==
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The line below this paragraph, containing "STRUCTURE_2rds", creates the "Structure Box" on the page.
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<StructureSection load='2rds' size='340' side='right'caption='[[2rds]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2rds]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_avermitilis Streptomyces avermitilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RDS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RDS FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PL:(1S,3AS,5AR,8AS)-1,7,7-TRIMETHYL-1,2,3,3A,5A,6,7,8-OCTAHYDROCYCLOPENTA[C]PENTALENE-4-CARBOXYLIC+ACID'>1PL</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=OGA:N-OXALYLGLYCINE'>OGA</scene></td></tr>
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{{STRUCTURE_2rds| PDB=2rds | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rds FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rds OCA], [https://pdbe.org/2rds PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rds RCSB], [https://www.ebi.ac.uk/pdbsum/2rds PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rds ProSAT]</span></td></tr>
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</table>
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===Crystal Structure of PtlH with Fe/oxalylglycine and ent-1-deoxypentalenic acid bound===
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== Function ==
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[https://www.uniprot.org/uniprot/PTLH_STRAW PTLH_STRAW] Catalyzes the conversion of 1-deoxypentalenic acid to 11-beta-hydroxy-1-deoxypentalenic acid in the biosynthesis of neopentalenolactone antibiotic.<ref>PMID:16704250</ref> <ref>PMID:17942405</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_17942405}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 17942405 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rd/2rds_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_17942405}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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2RDS is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_avermitilis Streptomyces avermitilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RDS OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2rds ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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Crystal structure of the non-heme iron dioxygenase PtlH in pentalenolactone biosynthesis., You Z, Omura S, Ikeda H, Cane DE, Jogl G, J Biol Chem. 2007 Dec 14;282(50):36552-60. Epub 2007 Oct 16. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17942405 17942405]
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<references/>
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[[Category: Single protein]]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Streptomyces avermitilis]]
[[Category: Streptomyces avermitilis]]
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[[Category: Cane, D E.]]
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[[Category: Cane DE]]
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[[Category: Ikeda, H.]]
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[[Category: Ikeda H]]
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[[Category: Jogl, G.]]
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[[Category: Jogl G]]
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[[Category: Omura, S.]]
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[[Category: Omura S]]
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[[Category: You, Z.]]
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[[Category: You Z]]
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[[Category: Dioxygenase]]
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[[Category: Double stranded barrel helix]]
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[[Category: Oxidoreductase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 19:32:48 2008''
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Current revision

Crystal Structure of PtlH with Fe/oxalylglycine and ent-1-deoxypentalenic acid bound

PDB ID 2rds

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