2dkd

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{{Seed}}
 
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[[Image:2dkd.png|left|200px]]
 
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==Crystal structure of N-acetylglucosamine-phosphate mutase, a member of the alpha-D-phosphohexomutase superfamily, in the product complex==
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The line below this paragraph, containing "STRUCTURE_2dkd", creates the "Structure Box" on the page.
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<StructureSection load='2dkd' size='340' side='right'caption='[[2dkd]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2dkd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Candida_albicans Candida albicans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DKD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DKD FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NG1:N-ACETYL-ALPHA-D-GALACTOSAMINE+1-PHOSPHATE'>NG1</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_2dkd| PDB=2dkd | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dkd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dkd OCA], [https://pdbe.org/2dkd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dkd RCSB], [https://www.ebi.ac.uk/pdbsum/2dkd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dkd ProSAT]</span></td></tr>
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</table>
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===Crystal structure of N-acetylglucosamine-phosphate mutase, a member of the alpha-D-phosphohexomutase superfamily, in the product complex===
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== Function ==
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[https://www.uniprot.org/uniprot/AGM1_CANAX AGM1_CANAX] Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins.<ref>PMID:11004509</ref>
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== Evolutionary Conservation ==
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 16651269 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dk/2dkd_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_16651269}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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2DKD is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Candida_albicans Candida albicans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DKD OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dkd ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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Crystal structures of N-acetylglucosamine-phosphate mutase, a member of the alpha-D-phosphohexomutase superfamily, and its substrate and product complexes., Nishitani Y, Maruyama D, Nonaka T, Kita A, Fukami TA, Mio T, Yamada-Okabe H, Yamada-Okabe T, Miki K, J Biol Chem. 2006 Jul 14;281(28):19740-7. Epub 2006 May 1. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16651269 16651269]
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<references/>
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__TOC__
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</StructureSection>
[[Category: Candida albicans]]
[[Category: Candida albicans]]
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[[Category: Phosphoacetylglucosamine mutase]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Fukami TA]]
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[[Category: Fukami, T A.]]
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[[Category: Kita A]]
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[[Category: Kita, A.]]
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[[Category: Maruyama D]]
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[[Category: Maruyama, D.]]
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[[Category: Miki K]]
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[[Category: Miki, K.]]
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[[Category: Mio T]]
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[[Category: Mio, T.]]
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[[Category: Nishitani Y]]
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[[Category: Nishitani, Y.]]
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[[Category: Nonaka T]]
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[[Category: Nonaka, T.]]
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[[Category: Yamada-Okabe H]]
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[[Category: Yamada-Okabe, H.]]
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[[Category: Yamada-Okabe T]]
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[[Category: Yamada-Okabe, T.]]
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[[Category: Mutase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 20:08:20 2008''
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Current revision

Crystal structure of N-acetylglucosamine-phosphate mutase, a member of the alpha-D-phosphohexomutase superfamily, in the product complex

PDB ID 2dkd

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