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1zvt

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{{Seed}}
 
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[[Image:1zvt.png|left|200px]]
 
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<!--
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==Structure of the E. coli ParC C-terminal domain==
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The line below this paragraph, containing "STRUCTURE_1zvt", creates the "Structure Box" on the page.
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<StructureSection load='1zvt' size='340' side='right'caption='[[1zvt]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1zvt]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZVT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZVT FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zvt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zvt OCA], [https://pdbe.org/1zvt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zvt RCSB], [https://www.ebi.ac.uk/pdbsum/1zvt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zvt ProSAT]</span></td></tr>
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{{STRUCTURE_1zvt| PDB=1zvt | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PARC_ECOLI PARC_ECOLI] Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule. MukB stimulates the relaxation activity of topoisomerase IV and also has a modest effect on decatenation.<ref>PMID:20921377</ref> <ref>PMID:12269820</ref> <ref>PMID:21300644</ref> <ref>PMID:16023670</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zv/1zvt_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1zvt ConSurf].
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<div style="clear:both"></div>
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===Structure of the E. coli ParC C-terminal domain===
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==See Also==
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*[[Topoisomerase 3D structures|Topoisomerase 3D structures]]
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== References ==
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<!--
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_16023670}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 16023670 is the PubMed ID number.
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</StructureSection>
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-->
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{{ABSTRACT_PUBMED_16023670}}
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==About this Structure==
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1ZVT is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZVT OCA].
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==Reference==
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The structural basis for substrate specificity in DNA topoisomerase IV., Corbett KD, Schoeffler AJ, Thomsen ND, Berger JM, J Mol Biol. 2005 Aug 19;351(3):545-61. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16023670 16023670]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Berger, J M.]]
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[[Category: Berger JM]]
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[[Category: Corbett, K D.]]
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[[Category: Corbett KD]]
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[[Category: Schoeffler, A J.]]
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[[Category: Schoeffler AJ]]
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[[Category: Thomsen, N D.]]
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[[Category: Thomsen ND]]
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[[Category: Atpase]]
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[[Category: Beta-pinwheel]]
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[[Category: Decatenation]]
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[[Category: Dna binding]]
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[[Category: Dna topology]]
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[[Category: Supercoiling]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 20:34:14 2008''
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Current revision

Structure of the E. coli ParC C-terminal domain

PDB ID 1zvt

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