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2ohh

From Proteopedia

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{{Seed}}
 
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[[Image:2ohh.png|left|200px]]
 
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==Crystal Structure of coenzyme F420H2 oxidase (FprA), a diiron flavoprotein, active oxidized state==
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The line below this paragraph, containing "STRUCTURE_2ohh", creates the "Structure Box" on the page.
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<StructureSection load='2ohh' size='340' side='right'caption='[[2ohh]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2ohh]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus Methanothermobacter thermautotrophicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OHH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OHH FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_2ohh| PDB=2ohh | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ohh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ohh OCA], [https://pdbe.org/2ohh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ohh RCSB], [https://www.ebi.ac.uk/pdbsum/2ohh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ohh ProSAT]</span></td></tr>
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</table>
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===Crystal Structure of coenzyme F420H2 oxidase (FprA), a diiron flavoprotein, active oxidized state===
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== Function ==
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[https://www.uniprot.org/uniprot/FPRA_METTM FPRA_METTM] Probably functions as an electron acceptor for a hydrogenase; however there is an uncharacterized intermediate between the hydrogenase and flavoprotein A.<ref>PMID:9660187</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 17480207 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oh/2ohh_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_17480207}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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2OHH is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus Methanothermobacter thermautotrophicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OHH OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ohh ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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Structure of coenzyme F420H2 oxidase (FprA), a di-iron flavoprotein from methanogenic Archaea catalyzing the reduction of O2 to H2O., Seedorf H, Hagemeier CH, Shima S, Thauer RK, Warkentin E, Ermler U, FEBS J. 2007 Mar;274(6):1588-99. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17480207 17480207]
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Methanothermobacter thermautotrophicus]]
[[Category: Methanothermobacter thermautotrophicus]]
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[[Category: Single protein]]
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[[Category: Ermler U]]
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[[Category: Ermler, U.]]
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[[Category: Seedorf H]]
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[[Category: Seedorf, H.]]
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[[Category: Warkentin E]]
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[[Category: Warkentin, E.]]
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[[Category: Beta-lactamase like domain]]
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[[Category: Flavodoxine like domain]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 20:44:24 2008''
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Current revision

Crystal Structure of coenzyme F420H2 oxidase (FprA), a diiron flavoprotein, active oxidized state

PDB ID 2ohh

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