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2izl

From Proteopedia

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{{Seed}}
 
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[[Image:2izl.png|left|200px]]
 
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==STREPTAVIDIN-2-IMINOBIOTIN PH 7.3 I222 COMPLEX==
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The line below this paragraph, containing "STRUCTURE_2izl", creates the "Structure Box" on the page.
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<StructureSection load='2izl' size='340' side='right'caption='[[2izl]], [[Resolution|resolution]] 1.48&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2izl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_avidinii Streptomyces avidinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IZL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IZL FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.48&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IMI:2-IMINOBIOTIN'>IMI</scene></td></tr>
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{{STRUCTURE_2izl| PDB=2izl | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2izl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2izl OCA], [https://pdbe.org/2izl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2izl RCSB], [https://www.ebi.ac.uk/pdbsum/2izl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2izl ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SAV_STRAV SAV_STRAV] The biological function of streptavidin is not known. Forms a strong non-covalent specific complex with biotin (one molecule of biotin per subunit of streptavidin).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iz/2izl_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2izl ConSurf].
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<div style="clear:both"></div>
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===STREPTAVIDIN-2-IMINOBIOTIN PH 7.3 I222 COMPLEX===
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==See Also==
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*[[Avidin 3D structures|Avidin 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_9405158}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 9405158 is the PubMed ID number.
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{{ABSTRACT_PUBMED_9405158}}
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==About this Structure==
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2IZL is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_avidinii Streptomyces avidinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IZL OCA].
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==Reference==
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Binding of biotin to streptavidin stabilizes intersubunit salt bridges between Asp61 and His87 at low pH., Katz BA, J Mol Biol. 1997 Dec 19;274(5):776-800. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9405158 9405158]
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[[Category: Single protein]]
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[[Category: Streptomyces avidinii]]
[[Category: Streptomyces avidinii]]
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[[Category: Katz, B A.]]
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[[Category: Katz BA]]
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[[Category: Biotin-binding protein]]
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[[Category: Streptavidin-2-iminobiotin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 20:59:52 2008''
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Current revision

STREPTAVIDIN-2-IMINOBIOTIN PH 7.3 I222 COMPLEX

PDB ID 2izl

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