2gac

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{{Seed}}
 
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[[Image:2gac.png|left|200px]]
 
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==T152C MUTANT GLYCOSYLASPARAGINASE FROM FLAVOBACTERIUM MENINGOSEPTICUM==
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The line below this paragraph, containing "STRUCTURE_2gac", creates the "Structure Box" on the page.
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<StructureSection load='2gac' size='340' side='right'caption='[[2gac]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2gac]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Elizabethkingia_meningoseptica Elizabethkingia meningoseptica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GAC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GAC FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gac FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gac OCA], [https://pdbe.org/2gac PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gac RCSB], [https://www.ebi.ac.uk/pdbsum/2gac PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gac ProSAT]</span></td></tr>
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{{STRUCTURE_2gac| PDB=2gac | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ASPG_ELIMR ASPG_ELIMR] Cleaves the GlcNAc-Asn bond which joins oligosaccharides to the peptide of asparagine-linked glycoproteins. Requires that the glycosylated asparagine moiety is not substituted on its N-(R1) and C- (R2) terminus.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ga/2gac_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gac ConSurf].
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<div style="clear:both"></div>
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===T152C MUTANT GLYCOSYLASPARAGINASE FROM FLAVOBACTERIUM MENINGOSEPTICUM===
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==See Also==
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*[[Glycosylasparaginase|Glycosylasparaginase]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_9685368}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 9685368 is the PubMed ID number.
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{{ABSTRACT_PUBMED_9685368}}
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==About this Structure==
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2GAC is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Elizabethkingia_meningoseptica Elizabethkingia meningoseptica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GAC OCA].
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==Reference==
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Crystal structures of Flavobacterium glycosylasparaginase. An N-terminal nucleophile hydrolase activated by intramolecular proteolysis., Guo HC, Xu Q, Buckley D, Guan C, J Biol Chem. 1998 Aug 7;273(32):20205-12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9685368 9685368]
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[[Category: Elizabethkingia meningoseptica]]
[[Category: Elizabethkingia meningoseptica]]
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[[Category: Protein complex]]
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[[Category: Large Structures]]
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[[Category: Guo, H C.]]
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[[Category: Guo H-C]]
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[[Category: Xu, Q.]]
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[[Category: Xu Q]]
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[[Category: Autoproteolysis]]
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[[Category: Glycosylasparaginase]]
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[[Category: Mutant]]
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[[Category: N-terminal nucleophile hydrolase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 21:07:18 2008''
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Current revision

T152C MUTANT GLYCOSYLASPARAGINASE FROM FLAVOBACTERIUM MENINGOSEPTICUM

PDB ID 2gac

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