1sx4

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{{Seed}}
 
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[[Image:1sx4.png|left|200px]]
 
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==GroEL-GroES-ADP7==
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The line below this paragraph, containing "STRUCTURE_1sx4", creates the "Structure Box" on the page.
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<StructureSection load='1sx4' size='340' side='right'caption='[[1sx4]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1sx4]] is a 21 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SX4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SX4 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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{{STRUCTURE_1sx4| PDB=1sx4 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sx4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sx4 OCA], [https://pdbe.org/1sx4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sx4 RCSB], [https://www.ebi.ac.uk/pdbsum/1sx4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sx4 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CH60_ECOLI CH60_ECOLI] Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.[HAMAP-Rule:MF_00600] Essential for the growth of the bacteria and the assembly of several bacteriophages. Also plays a role in coupling between replication of the F plasmid and cell division of the cell.[HAMAP-Rule:MF_00600]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sx/1sx4_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1sx4 ConSurf].
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<div style="clear:both"></div>
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===GroEL-GroES-ADP7===
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==See Also==
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*[[Chaperonin 3D structures|Chaperonin 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_15313620}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 15313620 is the PubMed ID number.
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{{ABSTRACT_PUBMED_15313620}}
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==About this Structure==
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1SX4 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SX4 OCA].
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==Reference==
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Exploring the structural dynamics of the E.coli chaperonin GroEL using translation-libration-screw crystallographic refinement of intermediate states., Chaudhry C, Horwich AL, Brunger AT, Adams PD, J Mol Biol. 2004 Sep 3;342(1):229-45. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15313620 15313620]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Protein complex]]
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[[Category: Large Structures]]
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[[Category: Adams, P D.]]
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[[Category: Adams PD]]
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[[Category: Brunger, A T.]]
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[[Category: Brunger AT]]
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[[Category: Chaudhry, C.]]
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[[Category: Chaudhry C]]
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[[Category: Horwich, A L.]]
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[[Category: Horwich AL]]
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[[Category: Molecular chaperone]]
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[[Category: Protein folding]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 21:10:54 2008''
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Current revision

GroEL-GroES-ADP7

PDB ID 1sx4

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