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2fq3

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{{Seed}}
 
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[[Image:2fq3.png|left|200px]]
 
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==Structure and function of the SWIRM domain, a conserved protein module found in chromatin regulatory complexes==
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The line below this paragraph, containing "STRUCTURE_2fq3", creates the "Structure Box" on the page.
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<StructureSection load='2fq3' size='340' side='right'caption='[[2fq3]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2fq3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FQ3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FQ3 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fq3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fq3 OCA], [https://pdbe.org/2fq3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fq3 RCSB], [https://www.ebi.ac.uk/pdbsum/2fq3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fq3 ProSAT]</span></td></tr>
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{{STRUCTURE_2fq3| PDB=2fq3 | SCENE= }}
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</table>
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== Function ==
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===Structure and function of the SWIRM domain, a conserved protein module found in chromatin regulatory complexes===
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[https://www.uniprot.org/uniprot/SWI3_YEAST SWI3_YEAST] Involved in transcriptional activation. Component of the SWI/SNF complex, an ATP-dependent chromatin-remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_16461455}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 16461455 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fq/2fq3_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_16461455}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fq3 ConSurf].
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2FQ3 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FQ3 OCA].
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<div style="clear:both"></div>
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__TOC__
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==Reference==
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</StructureSection>
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Structure and function of the SWIRM domain, a conserved protein module found in chromatin regulatory complexes., Da G, Lenkart J, Zhao K, Shiekhattar R, Cairns BR, Marmorstein R, Proc Natl Acad Sci U S A. 2006 Feb 14;103(7):2057-62. Epub 2006 Feb 3. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16461455 16461455]
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[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Single protein]]
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[[Category: Cairns BR]]
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[[Category: Cairns, B R.]]
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[[Category: Da G]]
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[[Category: Da, G.]]
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[[Category: Lenkart J]]
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[[Category: Lenkart, J.]]
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[[Category: Marmorstein R]]
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[[Category: Marmorstein, R.]]
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[[Category: Shiekhattar R]]
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[[Category: Shiekhattar, R.]]
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[[Category: Zhao K]]
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[[Category: Zhao, K.]]
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[[Category: Four-helix bundle]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 21:31:15 2008''
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Current revision

Structure and function of the SWIRM domain, a conserved protein module found in chromatin regulatory complexes

PDB ID 2fq3

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