1nxg

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{{Seed}}
 
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[[Image:1nxg.png|left|200px]]
 
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==The F383A variant of type II Citrate Synthase complexed with NADH==
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The line below this paragraph, containing "STRUCTURE_1nxg", creates the "Structure Box" on the page.
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<StructureSection load='1nxg' size='340' side='right'caption='[[1nxg]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1nxg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NXG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NXG FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAI:1,4-DIHYDRONICOTINAMIDE+ADENINE+DINUCLEOTIDE'>NAI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_1nxg| PDB=1nxg | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nxg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nxg OCA], [https://pdbe.org/1nxg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nxg RCSB], [https://www.ebi.ac.uk/pdbsum/1nxg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nxg ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CISY_ECOLI CISY_ECOLI]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nx/1nxg_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1nxg ConSurf].
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<div style="clear:both"></div>
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===The F383A variant of type II Citrate Synthase complexed with NADH===
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==See Also==
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*[[Citrate Synthase 3D structures|Citrate Synthase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_12741811}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 12741811 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12741811}}
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==About this Structure==
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1NXG is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NXG OCA].
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==Reference==
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Insights into the evolution of allosteric properties. The NADH binding site of hexameric type II citrate synthases., Maurus R, Nguyen NT, Stokell DJ, Ayed A, Hultin PG, Duckworth HW, Brayer GD, Biochemistry. 2003 May 20;42(19):5555-65. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12741811 12741811]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Ayed, A.]]
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[[Category: Ayed A]]
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[[Category: Brayer, G D.]]
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[[Category: Brayer GD]]
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[[Category: Duckworth, H W.]]
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[[Category: Duckworth HW]]
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[[Category: Hultin, P G.]]
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[[Category: Hultin PG]]
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[[Category: Maurus, R.]]
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[[Category: Maurus R]]
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[[Category: Nguyen, N T.]]
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[[Category: Nguyen NT]]
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[[Category: Stokell, D J.]]
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[[Category: Stokell DJ]]
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[[Category: Allosteric]]
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[[Category: Citrate synthase]]
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[[Category: F383a]]
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[[Category: Nadh]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 21:35:33 2008''
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Current revision

The F383A variant of type II Citrate Synthase complexed with NADH

PDB ID 1nxg

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