2p7v

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{{Seed}}
 
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[[Image:2p7v.png|left|200px]]
 
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==Crystal structure of the Escherichia coli regulator of sigma 70, Rsd, in complex with sigma 70 domain 4==
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The line below this paragraph, containing "STRUCTURE_2p7v", creates the "Structure Box" on the page.
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<StructureSection load='2p7v' size='340' side='right'caption='[[2p7v]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2p7v]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P7V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2P7V FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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{{STRUCTURE_2p7v| PDB=2p7v | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2p7v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p7v OCA], [https://pdbe.org/2p7v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2p7v RCSB], [https://www.ebi.ac.uk/pdbsum/2p7v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2p7v ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RSD_ECOLI RSD_ECOLI] Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase.<ref>PMID:9560209</ref> <ref>PMID:10368152</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p7/2p7v_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2p7v ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of the Escherichia coli regulator of sigma 70, Rsd, in complex with sigma 70 domain 4===
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==See Also==
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*[[Sigma factor 3D structures|Sigma factor 3D structures]]
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== References ==
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<references/>
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 17681541 is the PubMed ID number.
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</StructureSection>
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{{ABSTRACT_PUBMED_17681541}}
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==About this Structure==
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2P7V is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P7V OCA].
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==Reference==
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Crystal structure of the Escherichia coli regulator of sigma70, Rsd, in complex with sigma70 domain 4., Patikoglou GA, Westblade LF, Campbell EA, Lamour V, Lane WJ, Darst SA, J Mol Biol. 2007 Sep 21;372(3):649-59. Epub 2007 Jul 3. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17681541 17681541]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Protein complex]]
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[[Category: Large Structures]]
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[[Category: Campbell, E A.]]
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[[Category: Campbell EA]]
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[[Category: Darst, S A.]]
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[[Category: Darst SA]]
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[[Category: Lamour, V.]]
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[[Category: Lamour V]]
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[[Category: Lane, W J.]]
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[[Category: Lane WJ]]
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[[Category: Patikoglou, G A.]]
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[[Category: Patikoglou GA]]
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[[Category: Westblade, L F.]]
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[[Category: Westblade LF]]
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[[Category: E. coli rsd-sigma 70 complex]]
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[[Category: Escherichia coli rsd-sigma 70 complex]]
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[[Category: Helix-turn-helix]]
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[[Category: Regulation]]
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[[Category: Regulator of sigma 70]]
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[[Category: Rsd]]
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[[Category: Rsd-sigma 70 complex]]
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[[Category: Sigma 70]]
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[[Category: Sigma 70 domain 4]]
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[[Category: Sigma factor]]
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[[Category: Transcription]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 22:54:47 2008''
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Current revision

Crystal structure of the Escherichia coli regulator of sigma 70, Rsd, in complex with sigma 70 domain 4

PDB ID 2p7v

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