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1qb2

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{{Seed}}
 
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[[Image:1qb2.png|left|200px]]
 
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==CRYSTAL STRUCTURE OF THE CONSERVED SUBDOMAIN OF HUMAN PROTEIN SRP54M AT 2.1A RESOLUTION: EVIDENCE FOR THE MECHANISM OF SIGNAL PEPTIDE BINDING==
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The line below this paragraph, containing "STRUCTURE_1qb2", creates the "Structure Box" on the page.
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<StructureSection load='1qb2' size='340' side='right'caption='[[1qb2]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1qb2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QB2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QB2 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qb2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qb2 OCA], [https://pdbe.org/1qb2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qb2 RCSB], [https://www.ebi.ac.uk/pdbsum/1qb2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qb2 ProSAT]</span></td></tr>
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{{STRUCTURE_1qb2| PDB=1qb2 | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SRP54_HUMAN SRP54_HUMAN] Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qb/1qb2_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qb2 ConSurf].
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<div style="clear:both"></div>
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===CRYSTAL STRUCTURE OF THE CONSERVED SUBDOMAIN OF HUMAN PROTEIN SRP54M AT 2.1A RESOLUTION: EVIDENCE FOR THE MECHANISM OF SIGNAL PEPTIDE BINDING===
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==See Also==
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*[[Signal recognition particle 3D structures|Signal recognition particle 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_10497032}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 10497032 is the PubMed ID number.
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{{ABSTRACT_PUBMED_10497032}}
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==About this Structure==
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1QB2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QB2 OCA].
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==Reference==
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Crystal structure of the conserved subdomain of human protein SRP54M at 2.1 A resolution: evidence for the mechanism of signal peptide binding., Clemons WM Jr, Gowda K, Black SD, Zwieb C, Ramakrishnan V, J Mol Biol. 1999 Sep 24;292(3):697-705. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10497032 10497032]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Black, S D.]]
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[[Category: Black SD]]
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[[Category: Gowda, K.]]
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[[Category: Clemons Jr WM]]
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[[Category: Jr., W M.Clemons.]]
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[[Category: Gowda K]]
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[[Category: Ramakrishnan, V.]]
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[[Category: Ramakrishnan V]]
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[[Category: Zwieb, C.]]
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[[Category: Zwieb C]]
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[[Category: Alpha-helix]]
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[[Category: Helix-turn-helix]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 23:12:34 2008''
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Current revision

CRYSTAL STRUCTURE OF THE CONSERVED SUBDOMAIN OF HUMAN PROTEIN SRP54M AT 2.1A RESOLUTION: EVIDENCE FOR THE MECHANISM OF SIGNAL PEPTIDE BINDING

PDB ID 1qb2

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