1sd8

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{{Seed}}
 
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[[Image:1sd8.png|left|200px]]
 
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==ARSENATE REDUCTASE R60K MUTANT FROM E. COLI==
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The line below this paragraph, containing "STRUCTURE_1sd8", creates the "Structure Box" on the page.
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<StructureSection load='1sd8' size='340' side='right'caption='[[1sd8]], [[Resolution|resolution]] 1.59&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1sd8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SD8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SD8 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.59&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CS:CESIUM+ION'>CS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_1sd8| PDB=1sd8 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sd8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sd8 OCA], [https://pdbe.org/1sd8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sd8 RCSB], [https://www.ebi.ac.uk/pdbsum/1sd8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sd8 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ARSC1_ECOLX ARSC1_ECOLX] Reduction of arsenate [As(V)] to arsenite [As(III)]. This protein expands the substrate specificity of ArsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sd/1sd8_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1sd8 ConSurf].
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<div style="clear:both"></div>
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===ARSENATE REDUCTASE R60K MUTANT FROM E. COLI===
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==See Also==
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*[[Arsenate reductase 3D structures|Arsenate reductase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_15295115}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 15295115 is the PubMed ID number.
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{{ABSTRACT_PUBMED_15295115}}
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==About this Structure==
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1SD8 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SD8 OCA].
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==Reference==
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Arginine 60 in the ArsC arsenate reductase of E. coli plasmid R773 determines the chemical nature of the bound As(III) product., DeMel S, Shi J, Martin P, Rosen BP, Edwards BF, Protein Sci. 2004 Sep;13(9):2330-40. Epub 2004 Aug 4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15295115 15295115]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: DeMel, S.]]
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[[Category: DeMel S]]
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[[Category: Edwards, B F.]]
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[[Category: Edwards BF]]
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[[Category: Arsc]]
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[[Category: Arsenate]]
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[[Category: Arsenite]]
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[[Category: Reductase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 23:29:50 2008''
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Current revision

ARSENATE REDUCTASE R60K MUTANT FROM E. COLI

PDB ID 1sd8

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