1zym

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{{Seed}}
 
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[[Image:1zym.png|left|200px]]
 
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==AMINO TERMINAL DOMAIN OF ENZYME I FROM ESCHERICHIA COLI==
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The line below this paragraph, containing "STRUCTURE_1zym", creates the "Structure Box" on the page.
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<StructureSection load='1zym' size='340' side='right'caption='[[1zym]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1zym]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZYM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZYM FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zym FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zym OCA], [https://pdbe.org/1zym PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zym RCSB], [https://www.ebi.ac.uk/pdbsum/1zym PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zym ProSAT]</span></td></tr>
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{{STRUCTURE_1zym| PDB=1zym | SCENE= }}
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</table>
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== Function ==
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===AMINO TERMINAL DOMAIN OF ENZYME I FROM ESCHERICHIA COLI===
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[https://www.uniprot.org/uniprot/PT1_ECOLI PT1_ECOLI] General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).<ref>PMID:7876255</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_8805571}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 8805571 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zy/1zym_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_8805571}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1zym ConSurf].
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1ZYM is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZYM OCA].
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<div style="clear:both"></div>
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== References ==
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==Reference==
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<references/>
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The first step in sugar transport: crystal structure of the amino terminal domain of enzyme I of the E. coli PEP: sugar phosphotransferase system and a model of the phosphotransfer complex with HPr., Liao DI, Silverton E, Seok YJ, Lee BR, Peterkofsky A, Davies DR, Structure. 1996 Jul 15;4(7):861-72. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8805571 8805571]
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__TOC__
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Phosphoenolpyruvate--protein phosphotransferase]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Davies DR]]
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[[Category: Davies, D R.]]
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[[Category: Liao D-I]]
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[[Category: Liao, D I.]]
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[[Category: Phosphotransferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 23:46:04 2008''
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Current revision

AMINO TERMINAL DOMAIN OF ENZYME I FROM ESCHERICHIA COLI

PDB ID 1zym

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