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3b8i

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{{Seed}}
 
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[[Image:3b8i.png|left|200px]]
 
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==Crystal Structure of Oxaloacetate Decarboxylase from Pseudomonas Aeruginosa (PA4872) in complex with oxalate and Mg2+.==
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The line below this paragraph, containing "STRUCTURE_3b8i", creates the "Structure Box" on the page.
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<StructureSection load='3b8i' size='340' side='right'caption='[[3b8i]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3b8i]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B8I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3B8I FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=OXL:OXALATE+ION'>OXL</scene></td></tr>
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{{STRUCTURE_3b8i| PDB=3b8i | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3b8i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b8i OCA], [https://pdbe.org/3b8i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3b8i RCSB], [https://www.ebi.ac.uk/pdbsum/3b8i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3b8i ProSAT]</span></td></tr>
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</table>
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===Crystal Structure of Oxaloacetate Decarboxylase from Pseudomonas Aeruginosa (PA4872) in complex with oxalate and Mg2+.===
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== Function ==
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[https://www.uniprot.org/uniprot/OADC_PSEAE OADC_PSEAE] Catalyzes the decarboxylation of oxaloacetate into pyruvate with high efficiency. Is also able to decarboxylate 3-methyloxaloacetate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate.<ref>PMID:18081320</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 18081320 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b8/3b8i_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_18081320}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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3B8I is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B8I OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3b8i ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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Structure and function of PA4872 from Pseudomonas aeruginosa, a novel class of oxaloacetate decarboxylase from the PEP mutase/isocitrate lyase superfamily., Narayanan BC, Niu W, Han Y, Zou J, Mariano PS, Dunaway-Mariano D, Herzberg O, Biochemistry. 2008 Jan 8;47(1):167-82. Epub 2007 Dec 15. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18081320 18081320]
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<references/>
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[[Category: Oxaloacetate decarboxylase]]
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__TOC__
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[[Category: Pseudomonas aeruginosa]]
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</StructureSection>
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Herzberg, O]]
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[[Category: Pseudomonas aeruginosa PAO1]]
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[[Category: Narayanan, B C.]]
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[[Category: Herzberg O]]
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[[Category: Alpha/beta barrel]]
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[[Category: Narayanan BC]]
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[[Category: Helix swapping]]
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[[Category: Lyase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 23:48:00 2008''
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Current revision

Crystal Structure of Oxaloacetate Decarboxylase from Pseudomonas Aeruginosa (PA4872) in complex with oxalate and Mg2+.

PDB ID 3b8i

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