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2d11

From Proteopedia

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{{Seed}}
 
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[[Image:2d11.png|left|200px]]
 
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==Crystal structure of the Radixin FERM domain complexed with the NHERF-2 C-terminal tail peptide==
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The line below this paragraph, containing "STRUCTURE_2d11", creates the "Structure Box" on the page.
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<StructureSection load='2d11' size='340' side='right'caption='[[2d11]], [[Resolution|resolution]] 2.81&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2d11]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D11 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2D11 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.81&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d11 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d11 OCA], [https://pdbe.org/2d11 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d11 RCSB], [https://www.ebi.ac.uk/pdbsum/2d11 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d11 ProSAT]</span></td></tr>
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{{STRUCTURE_2d11| PDB=2d11 | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RADI_MOUSE RADI_MOUSE] Probably plays a crucial role in the binding of the barbed end of actin filaments to the plasma membrane.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d1/2d11_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2d11 ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of the Radixin FERM domain complexed with the NHERF-2 C-terminal tail peptide===
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==See Also==
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*[[Radixin|Radixin]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_16615918}}, adds the Publication Abstract to the page
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[[Category: Homo sapiens]]
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(as it appears on PubMed at http://www.pubmed.gov), where 16615918 is the PubMed ID number.
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_16615918}}
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==About this Structure==
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2D11 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D11 OCA].
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==Reference==
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Structural basis for NHERF recognition by ERM proteins., Terawaki S, Maesaki R, Hakoshima T, Structure. 2006 Apr;14(4):777-89. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16615918 16615918]
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Crystallographic characterization of the radixin FERM domain bound to the C-terminal region of the human Na+/H+-exchanger regulatory factor (NHERF)., Terawaki S, Maesaki R, Okada K, Hakoshima T, Acta Crystallogr D Biol Crystallogr. 2003 Jan;59(Pt 1):177-9. Epub 2002, Dec 19. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12499563 12499563]
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Structural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domain., Hamada K, Shimizu T, Matsui T, Tsukita S, Hakoshima T, EMBO J. 2000 Sep 1;19(17):4449-62. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10970839 10970839]
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Structural basis of adhesion-molecule recognition by ERM proteins revealed by the crystal structure of the radixin-ICAM-2 complex., Hamada K, Shimizu T, Yonemura S, Tsukita S, Tsukita S, Hakoshima T, EMBO J. 2003 Feb 3;22(3):502-14. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12554651 12554651]
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[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Protein complex]]
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[[Category: Hakoshima T]]
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[[Category: Hakoshima, T.]]
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[[Category: Maesaki R]]
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[[Category: Maesaki, R.]]
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[[Category: Terawaki S]]
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[[Category: Terawaki, S.]]
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[[Category: Protein-peptide complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 23:51:09 2008''
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Current revision

Crystal structure of the Radixin FERM domain complexed with the NHERF-2 C-terminal tail peptide

PDB ID 2d11

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