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1qnk

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{{Seed}}
 
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[[Image:1qnk.png|left|200px]]
 
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==TRUNCATED HUMAN GROB[5-73], NMR, 20 STRUCTURES==
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The line below this paragraph, containing "STRUCTURE_1qnk", creates the "Structure Box" on the page.
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<StructureSection load='1qnk' size='340' side='right'caption='[[1qnk]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1qnk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QNK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QNK FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qnk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qnk OCA], [https://pdbe.org/1qnk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qnk RCSB], [https://www.ebi.ac.uk/pdbsum/1qnk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qnk ProSAT]</span></td></tr>
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{{STRUCTURE_1qnk| PDB=1qnk | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CXCL2_HUMAN CXCL2_HUMAN] Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity.<ref>PMID:10725737</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qn/1qnk_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qnk ConSurf].
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<div style="clear:both"></div>
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===TRUNCATED HUMAN GROB[5-73], NMR, 20 STRUCTURES===
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==See Also==
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*[[C-X-C motif chemokine 3D structures|C-X-C motif chemokine 3D structures]]
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== References ==
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<!--
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_10600366}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 10600366 is the PubMed ID number.
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</StructureSection>
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-->
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{{ABSTRACT_PUBMED_10600366}}
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==About this Structure==
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1QNK is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QNK OCA].
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==Reference==
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Nuclear magnetic resonance solution structure of truncated human GRObeta [5-73] and its structural comparison with CXC chemokine family members GROalpha and IL-8., Qian YQ, Johanson KO, McDevitt P, J Mol Biol. 1999 Dec 17;294(5):1065-72. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10600366 10600366]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Johanson, K.]]
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[[Category: Johanson K]]
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[[Category: Mcdevitt, P.]]
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[[Category: McDevitt P]]
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[[Category: Qian, Y Q.]]
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[[Category: Qian YQ]]
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[[Category: Chemokine 15-o]]
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[[Category: Cxc chemokine]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 23:57:51 2008''
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Current revision

TRUNCATED HUMAN GROB[5-73], NMR, 20 STRUCTURES

PDB ID 1qnk

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