1tuw

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{{Seed}}
 
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[[Image:1tuw.png|left|200px]]
 
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==Structural and Functional Analysis of Tetracenomycin F2 Cyclase from Streptomyces glaucescens: A Type-II Polyketide Cyclase==
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The line below this paragraph, containing "STRUCTURE_1tuw", creates the "Structure Box" on the page.
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<StructureSection load='1tuw' size='340' side='right'caption='[[1tuw]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1tuw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_glaucescens Streptomyces glaucescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TUW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TUW FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_1tuw| PDB=1tuw | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tuw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tuw OCA], [https://pdbe.org/1tuw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tuw RCSB], [https://www.ebi.ac.uk/pdbsum/1tuw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tuw ProSAT]</span></td></tr>
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</table>
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===Structural and Functional Analysis of Tetracenomycin F2 Cyclase from Streptomyces glaucescens: A Type-II Polyketide Cyclase===
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== Function ==
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[https://www.uniprot.org/uniprot/TCMI_STRGA TCMI_STRGA] Required for conversion of tetracenomycin F2 to tetracenomycin D3.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_15231835}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 15231835 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tu/1tuw_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_15231835}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1TUW is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_glaucescens Streptomyces glaucescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TUW OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1tuw ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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Structural and functional analysis of tetracenomycin F2 cyclase from Streptomyces glaucescens. A type II polyketide cyclase., Thompson TB, Katayama K, Watanabe K, Hutchinson CR, Rayment I, J Biol Chem. 2004 Sep 3;279(36):37956-63. Epub 2004 Jun 30. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15231835 15231835]
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</StructureSection>
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[[Category: Single protein]]
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[[Category: Large Structures]]
[[Category: Streptomyces glaucescens]]
[[Category: Streptomyces glaucescens]]
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[[Category: Hutchinson, C R.]]
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[[Category: Hutchinson CR]]
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[[Category: Katayama, K.]]
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[[Category: Katayama K]]
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[[Category: Rayment, I.]]
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[[Category: Rayment I]]
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[[Category: Thompson, T B.]]
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[[Category: Thompson TB]]
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[[Category: Watanabe, K.]]
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[[Category: Watanabe K]]
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[[Category: Dimeric ??? ferredoxin-like fold tetracenomycin c biosynthesis]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 00:17:39 2008''
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Current revision

Structural and Functional Analysis of Tetracenomycin F2 Cyclase from Streptomyces glaucescens: A Type-II Polyketide Cyclase

PDB ID 1tuw

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