2ay0

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{{Seed}}
 
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[[Image:2ay0.png|left|200px]]
 
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==Structure of the Lys9Met mutant of the E. coli Proline Utilization A (PutA) DNA-binding domain.==
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The line below this paragraph, containing "STRUCTURE_2ay0", creates the "Structure Box" on the page.
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<StructureSection load='2ay0' size='340' side='right'caption='[[2ay0]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2ay0]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AY0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AY0 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
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{{STRUCTURE_2ay0| PDB=2ay0 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ay0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ay0 OCA], [https://pdbe.org/2ay0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ay0 RCSB], [https://www.ebi.ac.uk/pdbsum/2ay0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ay0 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PUTA_ECOLI PUTA_ECOLI] Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ay/2ay0_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ay0 ConSurf].
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<div style="clear:both"></div>
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===Structure of the Lys9Met mutant of the E. coli Proline Utilization A (PutA) DNA-binding domain.===
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==See Also==
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*[[Proline utilization A|Proline utilization A]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_17001030}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 17001030 is the PubMed ID number.
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{{ABSTRACT_PUBMED_17001030}}
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==About this Structure==
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2AY0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AY0 OCA].
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==Reference==
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Crystal structures of the DNA-binding domain of Escherichia coli proline utilization A flavoprotein and analysis of the role of Lys9 in DNA recognition., Larson JD, Jenkins JL, Schuermann JP, Zhou Y, Becker DF, Tanner JJ, Protein Sci. 2006 Nov;15(11):2630-41. Epub 2006 Sep 25. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17001030 17001030]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Becker, D F.]]
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[[Category: Becker DF]]
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[[Category: Jenkins, J L.]]
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[[Category: Jenkins JL]]
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[[Category: Larson, J D.]]
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[[Category: Larson JD]]
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[[Category: Schuermann, J P.]]
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[[Category: Schuermann JP]]
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[[Category: Tanner, J J.]]
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[[Category: Tanner JJ]]
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[[Category: Zhou, Y.]]
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[[Category: Zhou Y]]
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[[Category: Dna-binding domain]]
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[[Category: Proline catabolism]]
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[[Category: Proline utilization some]]
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[[Category: Puta]]
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[[Category: Ribbon-helix-helix]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 00:34:41 2008''
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Current revision

Structure of the Lys9Met mutant of the E. coli Proline Utilization A (PutA) DNA-binding domain.

PDB ID 2ay0

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OCA

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