This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1u2e

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (13:30, 13 March 2024) (edit) (undo)
 
(9 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1u2e.png|left|200px]]
 
-
<!--
+
==Crystal Structure of the C-C bond hydrolase MhpC==
-
The line below this paragraph, containing "STRUCTURE_1u2e", creates the "Structure Box" on the page.
+
<StructureSection load='1u2e' size='340' side='right'caption='[[1u2e]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1u2e]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U2E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1U2E FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
-
{{STRUCTURE_1u2e| PDB=1u2e | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1u2e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u2e OCA], [https://pdbe.org/1u2e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1u2e RCSB], [https://www.ebi.ac.uk/pdbsum/1u2e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1u2e ProSAT]</span></td></tr>
-
 
+
</table>
-
===Crystal Structure of the C-C bond hydrolase MhpC===
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/MHPC_ECOLI MHPC_ECOLI] Catalyzes the cleavage of the C5-C6 bond of 2-hydroxy-6-oxononadienedioate and 2-hydroxy-6-oxononatrienedioate, a dienol ring fission product of the bacterial meta-cleavage pathway for degradation of phenylpropionic acid. MhpC shows some selectivity for the carboxylate of the side chain.<ref>PMID:9098055</ref> <ref>PMID:9315862</ref>
-
 
+
== Evolutionary Conservation ==
-
<!--
+
[[Image:Consurf_key_small.gif|200px|right]]
-
The line below this paragraph, {{ABSTRACT_PUBMED_15663942}}, adds the Publication Abstract to the page
+
Check<jmol>
-
(as it appears on PubMed at http://www.pubmed.gov), where 15663942 is the PubMed ID number.
+
<jmolCheckbox>
-
-->
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/u2/1u2e_consurf.spt"</scriptWhenChecked>
-
{{ABSTRACT_PUBMED_15663942}}
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
 
+
<text>to colour the structure by Evolutionary Conservation</text>
-
==About this Structure==
+
</jmolCheckbox>
-
1U2E is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U2E OCA].
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1u2e ConSurf].
-
 
+
<div style="clear:both"></div>
-
==Reference==
+
== References ==
-
The structure of the C-C bond hydrolase MhpC provides insights into its catalytic mechanism., Dunn G, Montgomery MG, Mohammed F, Coker A, Cooper JB, Robertson T, Garcia JL, Bugg TD, Wood SP, J Mol Biol. 2005 Feb 11;346(1):253-65. Epub 2004 Dec 15. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15663942 15663942]
+
<references/>
 +
__TOC__
 +
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
-
[[Category: Single protein]]
+
[[Category: Large Structures]]
-
[[Category: Bugg, T D.H.]]
+
[[Category: Bugg TDH]]
-
[[Category: Coker, A.]]
+
[[Category: Coker A]]
-
[[Category: Dunn, G.]]
+
[[Category: Dunn G]]
-
[[Category: Garcia, J L.]]
+
[[Category: Garcia J-L]]
-
[[Category: Mohammed, F.]]
+
[[Category: Mohammed F]]
-
[[Category: Montgomery, M G.]]
+
[[Category: Montgomery MG]]
-
[[Category: Robertson, T.]]
+
[[Category: Robertson T]]
-
[[Category: Wood, S P.]]
+
[[Category: Wood SP]]
-
[[Category: Alpha/beta hydrolase fold]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 00:38:32 2008''
+

Current revision

Crystal Structure of the C-C bond hydrolase MhpC

PDB ID 1u2e

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1u2e"
Personal tools