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277d

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{{Seed}}
 
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[[Image:277d.png|left|200px]]
 
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==SUBSTITUTIONS AT C2' OF DAUNOSAMINE IN THE ANTICANCER DAUNORUBICIN ALTER ITS DNA-BINDING SEQUENCE SPECIFICITY==
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The line below this paragraph, containing "STRUCTURE_277d", creates the "Structure Box" on the page.
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<StructureSection load='277d' size='340' side='right'caption='[[277d]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[277d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=277D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=277D FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DM8:2-BROMO-4-EPIDAUNORUBICIN'>DM8</scene>, <scene name='pdbligand=G49:N2-METHYL-2-DEOXY-GUANOSINE-5-MONOPHOSPHATE'>G49</scene></td></tr>
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{{STRUCTURE_277d| PDB=277d | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=277d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=277d OCA], [https://pdbe.org/277d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=277d RCSB], [https://www.ebi.ac.uk/pdbsum/277d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=277d ProSAT]</span></td></tr>
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</table>
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===SUBSTITUTIONS AT C2' OF DAUNOSAMINE IN THE ANTICANCER DAUNORUBICIN ALTER ITS DNA-BINDING SEQUENCE SPECIFICITY===
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Gao Y-G]]
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The line below this paragraph, {{ABSTRACT_PUBMED_8841395}}, adds the Publication Abstract to the page
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[[Category: Priebe W]]
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(as it appears on PubMed at http://www.pubmed.gov), where 8841395 is the PubMed ID number.
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[[Category: Wang AH-J]]
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{{ABSTRACT_PUBMED_8841395}}
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==About this Structure==
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=277D OCA].
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==Reference==
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Substitutions at C2' of daunosamine in the anticancer drug daunorubicin alter its DNA-binding sequence specificity., Gao YG, Priebe W, Wang AH, Eur J Biochem. 1996 Sep 1;240(2):331-5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8841395 8841395]
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[[Category: Gao, Y G.]]
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[[Category: Priebe, W.]]
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[[Category: Wang, A H.J.]]
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[[Category: Complexed with drug]]
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[[Category: Double helix]]
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[[Category: Modified]]
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[[Category: Right handed dna]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 00:40:10 2008''
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Current revision

SUBSTITUTIONS AT C2' OF DAUNOSAMINE IN THE ANTICANCER DAUNORUBICIN ALTER ITS DNA-BINDING SEQUENCE SPECIFICITY

PDB ID 277d

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