1n1h

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{{Seed}}
 
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[[Image:1n1h.png|left|200px]]
 
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==Initiation complex of polymerase lambda3 from reovirus==
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The line below this paragraph, containing "STRUCTURE_1n1h", creates the "Structure Box" on the page.
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<StructureSection load='1n1h' size='340' side='right'caption='[[1n1h]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1n1h]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mammalian_orthoreovirus_3_Dearing Mammalian orthoreovirus 3 Dearing]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N1H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1N1H FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CH1:3-DEOXY-CYTIDINE-5-TRIPHOSPHATE'>CH1</scene>, <scene name='pdbligand=G7M:N7-METHYL-GUANOSINE-5-MONOPHOSPHATE'>G7M</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GH3:3-DEOXY-GUANOSINE-5-TRIPHOSPHATE'>GH3</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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{{STRUCTURE_1n1h| PDB=1n1h | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1n1h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n1h OCA], [https://pdbe.org/1n1h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1n1h RCSB], [https://www.ebi.ac.uk/pdbsum/1n1h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1n1h ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RDRP_REOVD RDRP_REOVD] RNA-directed RNA polymerase that is involved in transcription and genome replication. Following infection, it catalyzes the synthesis of fully conservative plus strands. After core assembly, which consists in recruitment of one capped plus-strand for each genomic segments and polymerase complexes, the polymerase switches mode and catalyzes the synthesis of complementary minus-strands.
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===Initiation complex of polymerase lambda3 from reovirus===
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==See Also==
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*[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_12464184}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 12464184 is the PubMed ID number.
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[[Category: Mammalian orthoreovirus 3 Dearing]]
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[[Category: Farsetta DL]]
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{{ABSTRACT_PUBMED_12464184}}
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[[Category: Harrison SC]]
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[[Category: Nibert ML]]
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==About this Structure==
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[[Category: Tao Y]]
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1N1H is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mammalian_orthoreovirus_3 Mammalian orthoreovirus 3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N1H OCA].
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==Reference==
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RNA synthesis in a cage--structural studies of reovirus polymerase lambda3., Tao Y, Farsetta DL, Nibert ML, Harrison SC, Cell. 2002 Nov 27;111(5):733-45. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12464184 12464184]
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[[Category: Mammalian orthoreovirus 3]]
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[[Category: Single protein]]
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[[Category: Farsetta, D L.]]
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[[Category: Harrison, S C.]]
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[[Category: Nibert, M L.]]
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[[Category: Tao, Y.]]
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[[Category: Initiation complex]]
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[[Category: Polymerase]]
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[[Category: Right hand configuration]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 00:49:49 2008''
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Current revision

Initiation complex of polymerase lambda3 from reovirus

PDB ID 1n1h

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