1r5t

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{{Seed}}
 
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[[Image:1r5t.png|left|200px]]
 
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==The Crystal Structure of Cytidine Deaminase CDD1, an Orphan C to U editase from Yeast==
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The line below this paragraph, containing "STRUCTURE_1r5t", creates the "Structure Box" on the page.
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<StructureSection load='1r5t' size='340' side='right'caption='[[1r5t]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1r5t]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R5T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1R5T FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_1r5t| PDB=1r5t | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1r5t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r5t OCA], [https://pdbe.org/1r5t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1r5t RCSB], [https://www.ebi.ac.uk/pdbsum/1r5t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1r5t ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CDD_YEAST CDD_YEAST] This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r5/1r5t_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1r5t ConSurf].
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<div style="clear:both"></div>
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===The Crystal Structure of Cytidine Deaminase CDD1, an Orphan C to U editase from Yeast===
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==See Also==
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*[[Deaminase 3D structures|Deaminase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_15148397}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 15148397 is the PubMed ID number.
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{{ABSTRACT_PUBMED_15148397}}
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==About this Structure==
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1R5T is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R5T OCA].
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==Reference==
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The structure of a yeast RNA-editing deaminase provides insight into the fold and function of activation-induced deaminase and APOBEC-1., Xie K, Sowden MP, Dance GS, Torelli AT, Smith HC, Wedekind JE, Proc Natl Acad Sci U S A. 2004 May 25;101(21):8114-9. Epub 2004 May 17. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15148397 15148397]
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[[Category: Cytidine deaminase]]
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[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Single protein]]
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[[Category: Dance GSC]]
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[[Category: Dance, G S.C.]]
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[[Category: Smith HC]]
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[[Category: Smith, H C.]]
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[[Category: Sowden MP]]
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[[Category: Sowden, M P.]]
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[[Category: Torelli AT]]
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[[Category: Torelli, A T.]]
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[[Category: Wedekind JE]]
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[[Category: Wedekind, J E.]]
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[[Category: Xie K]]
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[[Category: Xie, K.]]
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[[Category: Apobec-1 related protein]]
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[[Category: Rna editing]]
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[[Category: Zinc dependent deaminase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 01:54:56 2008''
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Current revision

The Crystal Structure of Cytidine Deaminase CDD1, an Orphan C to U editase from Yeast

PDB ID 1r5t

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