2qsq

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{{Seed}}
 
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[[Image:2qsq.png|left|200px]]
 
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==Crystal structure of the N-terminal domain of carcinoembryonic antigen (CEA)==
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The line below this paragraph, containing "STRUCTURE_2qsq", creates the "Structure Box" on the page.
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<StructureSection load='2qsq' size='340' side='right'caption='[[2qsq]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2qsq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QSQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QSQ FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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{{STRUCTURE_2qsq| PDB=2qsq | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qsq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qsq OCA], [https://pdbe.org/2qsq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qsq RCSB], [https://www.ebi.ac.uk/pdbsum/2qsq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qsq ProSAT]</span></td></tr>
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</table>
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===Crystal structure of the N-terminal domain of carcinoembryonic antigen (CEA)===
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== Function ==
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[https://www.uniprot.org/uniprot/CEAM5_HUMAN CEAM5_HUMAN] Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins.<ref>PMID:10864933</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_18086185}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 18086185 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qs/2qsq_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_18086185}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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2QSQ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QSQ OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qsq ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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Binding of Dr adhesins of Escherichia coli to carcinoembryonic antigen triggers receptor dissociation., Korotkova N, Yang Y, Le Trong I, Cota E, Demeler B, Marchant J, Thomas WE, Stenkamp RE, Moseley SL, Matthews S, Mol Microbiol. 2008 Jan;67(2):420-34. Epub 2007 Dec 11. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18086185 18086185]
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<references/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Korotkova, N.]]
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[[Category: Korotkova N]]
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[[Category: Moseley, S L.]]
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[[Category: Le Trong I]]
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[[Category: Stenkamp, R E.]]
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[[Category: Moseley SL]]
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[[Category: Trong, I Le.]]
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[[Category: Stenkamp RE]]
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[[Category: Cell adhesion]]
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[[Category: Glycoprotein]]
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[[Category: Gpi-anchor]]
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[[Category: Immunoglobulin domain]]
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[[Category: Lipoprotein]]
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[[Category: Membrane]]
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[[Category: Polymorphism]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 02:22:02 2008''
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Current revision

Crystal structure of the N-terminal domain of carcinoembryonic antigen (CEA)

PDB ID 2qsq

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