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1nne

From Proteopedia

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{{Seed}}
 
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[[Image:1nne.png|left|200px]]
 
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==Crystal Structure of the MutS-ADPBeF3-DNA complex==
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The line below this paragraph, containing "STRUCTURE_1nne", creates the "Structure Box" on the page.
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<StructureSection load='1nne' size='340' side='right'caption='[[1nne]], [[Resolution|resolution]] 3.11&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1nne]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_aquaticus Thermus aquaticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NNE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NNE FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.11&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=BEF:BERYLLIUM+TRIFLUORIDE+ION'>BEF</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_1nne| PDB=1nne | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nne FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nne OCA], [https://pdbe.org/1nne PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nne RCSB], [https://www.ebi.ac.uk/pdbsum/1nne PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nne ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/MUTS_THEAQ MUTS_THEAQ] This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nn/1nne_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1nne ConSurf].
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<div style="clear:both"></div>
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===Crystal Structure of the MutS-ADPBeF3-DNA complex===
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==See Also==
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*[[DNA mismatch repair protein 3D structures|DNA mismatch repair protein 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_12582174}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 12582174 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12582174}}
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==About this Structure==
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1NNE is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_aquaticus Thermus aquaticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NNE OCA].
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==Reference==
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Crystal structure and biochemical analysis of the MutS.ADP.beryllium fluoride complex suggests a conserved mechanism for ATP interactions in mismatch repair., Alani E, Lee JY, Schofield MJ, Kijas AW, Hsieh P, Yang W, J Biol Chem. 2003 May 2;278(18):16088-94. Epub 2003 Feb 11. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12582174 12582174]
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[[Category: Single protein]]
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[[Category: Thermus aquaticus]]
[[Category: Thermus aquaticus]]
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[[Category: Alani, E.]]
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[[Category: Alani E]]
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[[Category: Hsieh, P.]]
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[[Category: Hsieh P]]
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[[Category: Kijas, A W.]]
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[[Category: Kijas AW]]
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[[Category: Lee, J Y.]]
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[[Category: Lee JY]]
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[[Category: Schofield, M J.]]
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[[Category: Schofield MJ]]
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[[Category: Yang, W.]]
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[[Category: Yang W]]
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[[Category: Dna]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 02:36:28 2008''
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Current revision

Crystal Structure of the MutS-ADPBeF3-DNA complex

PDB ID 1nne

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