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1otg

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{{Seed}}
 
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[[Image:1otg.png|left|200px]]
 
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<!--
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==5-CARBOXYMETHYL-2-HYDROXYMUCONATE ISOMERASE==
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The line below this paragraph, containing "STRUCTURE_1otg", creates the "Structure Box" on the page.
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<StructureSection load='1otg' size='340' side='right'caption='[[1otg]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1otg]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_C Escherichia coli C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OTG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OTG FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_1otg| PDB=1otg | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1otg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1otg OCA], [https://pdbe.org/1otg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1otg RCSB], [https://www.ebi.ac.uk/pdbsum/1otg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1otg ProSAT]</span></td></tr>
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</table>
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===5-CARBOXYMETHYL-2-HYDROXYMUCONATE ISOMERASE===
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== Function ==
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[https://www.uniprot.org/uniprot/HPCD_ECOLX HPCD_ECOLX] Transforms 5-carboxymethyl-2-hydroxy-muconic acid (CHM) into 5-oxo-pent-3-ene-1,2,5-tricarboxylic acid (OPET).
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== Evolutionary Conservation ==
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<!--
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_8547259}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 8547259 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ot/1otg_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_8547259}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1OTG is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OTG OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1otg ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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Enzymatic ketonization of 2-hydroxymuconate: specificity and mechanism investigated by the crystal structures of two isomerases., Subramanya HS, Roper DI, Dauter Z, Dodson EJ, Davies GJ, Wilson KS, Wigley DB, Biochemistry. 1996 Jan 23;35(3):792-802. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8547259 8547259]
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</StructureSection>
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[[Category: Escherichia coli]]
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[[Category: Escherichia coli C]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Dauter, Z.]]
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[[Category: Dauter Z]]
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[[Category: Davies, G J.]]
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[[Category: Davies GJ]]
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[[Category: Dodson, E J.]]
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[[Category: Dodson EJ]]
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[[Category: Roper, D I.]]
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[[Category: Roper DI]]
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[[Category: Subramanya, H S.]]
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[[Category: Subramanya HS]]
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[[Category: Wigley, D B.]]
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[[Category: Wigley DB]]
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[[Category: Wilson, K S.]]
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[[Category: Wilson KS]]
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[[Category: Hydroxymuconate]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 02:57:12 2008''
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Current revision

5-CARBOXYMETHYL-2-HYDROXYMUCONATE ISOMERASE

PDB ID 1otg

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