2hdd

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:32, 14 February 2024) (edit) (undo)
 
(10 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:2hdd.png|left|200px]]
 
-
<!--
+
==ENGRAILED HOMEODOMAIN Q50K VARIANT DNA COMPLEX==
-
The line below this paragraph, containing "STRUCTURE_2hdd", creates the "Structure Box" on the page.
+
<StructureSection load='2hdd' size='340' side='right'caption='[[2hdd]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2hdd]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HDD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HDD FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-
-->
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hdd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hdd OCA], [https://pdbe.org/2hdd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hdd RCSB], [https://www.ebi.ac.uk/pdbsum/2hdd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hdd ProSAT]</span></td></tr>
-
{{STRUCTURE_2hdd| PDB=2hdd | SCENE= }}
+
</table>
-
 
+
== Function ==
-
===ENGRAILED HOMEODOMAIN Q50K VARIANT DNA COMPLEX===
+
[https://www.uniprot.org/uniprot/HMEN_DROME HMEN_DROME] This protein specifies the body segmentation pattern. It is required for the development of the central nervous system. Transcriptional regulator that represses activated promoters. Wg signaling operates by inactivating the SGG repression of EN autoactivation.
-
 
+
== Evolutionary Conservation ==
-
 
+
[[Image:Consurf_key_small.gif|200px|right]]
-
<!--
+
Check<jmol>
-
The line below this paragraph, {{ABSTRACT_PUBMED_9309220}}, adds the Publication Abstract to the page
+
<jmolCheckbox>
-
(as it appears on PubMed at http://www.pubmed.gov), where 9309220 is the PubMed ID number.
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hd/2hdd_consurf.spt"</scriptWhenChecked>
-
-->
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
{{ABSTRACT_PUBMED_9309220}}
+
<text>to colour the structure by Evolutionary Conservation</text>
-
 
+
</jmolCheckbox>
-
==About this Structure==
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hdd ConSurf].
-
2HDD is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HDD OCA].
+
<div style="clear:both"></div>
-
 
+
__TOC__
-
==Reference==
+
</StructureSection>
-
Engrailed (Gln50--&gt;Lys) homeodomain-DNA complex at 1.9 A resolution: structural basis for enhanced affinity and altered specificity., Tucker-Kellogg L, Rould MA, Chambers KA, Ades SE, Sauer RT, Pabo CO, Structure. 1997 Aug 15;5(8):1047-54. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9309220 9309220]
+
[[Category: Drosophila melanogaster]]
[[Category: Drosophila melanogaster]]
-
[[Category: Single protein]]
+
[[Category: Large Structures]]
-
[[Category: Ades, S E.]]
+
[[Category: Ades SE]]
-
[[Category: Chambers, K A.]]
+
[[Category: Chambers KA]]
-
[[Category: Pabo, C O.]]
+
[[Category: Pabo CO]]
-
[[Category: Rould, M A.]]
+
[[Category: Rould MA]]
-
[[Category: Sauer, R T.]]
+
[[Category: Sauer RT]]
-
[[Category: Tucker-Kellogg, L.]]
+
[[Category: Tucker-Kellogg L]]
-
[[Category: Dna binding]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 03:15:58 2008''
+

Current revision

ENGRAILED HOMEODOMAIN Q50K VARIANT DNA COMPLEX

PDB ID 2hdd

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2hdd"
Personal tools