2a5w

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{{Seed}}
 
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[[Image:2a5w.png|left|200px]]
 
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==Crystal structure of the oxidized gamma-subunit of the dissimilatory sulfite reductase (DsrC) from Archaeoglobus fulgidus==
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The line below this paragraph, containing "STRUCTURE_2a5w", creates the "Structure Box" on the page.
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<StructureSection load='2a5w' size='340' side='right'caption='[[2a5w]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2a5w]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Archaeoglobus_fulgidus_DSM_4304 Archaeoglobus fulgidus DSM 4304]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A5W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2A5W FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_2a5w| PDB=2a5w | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2a5w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a5w OCA], [https://pdbe.org/2a5w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2a5w RCSB], [https://www.ebi.ac.uk/pdbsum/2a5w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2a5w ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/O28055_ARCFU O28055_ARCFU]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a5/2a5w_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2a5w ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The X-ray structure of the gamma-subunit of the dissimilatory sulfite reductase (DsrC) from Archaeoglobus fulgidus was determined at 1.12 and 2.1A resolution, in the two crystal forms named DsrC(nat) and DsrC(ox) the latter being cocrystallized with the oxidizing agent tert-butyl hydroperoxide. The fold corresponds to that of the homologous protein from Pyrobaculum aerophilum but is significantly more compact. The most interesting, highly conserved C-terminal arm adopts a well-defined conformation in A. fulgidus DsrC in contrast to the completely disordered conformation in P. aerophilum DsrC. The functional relevance of both conformations and of a potentially redox-active disulfide bond between the strictly invariant Cys103 and Cys114 are discussed.
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===Crystal structure of the oxidized gamma-subunit of the dissimilatory sulfite reductase (DsrC) from Archaeoglobus fulgidus===
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X-ray structure of the gamma-subunit of a dissimilatory sulfite reductase: fixed and flexible C-terminal arms.,Mander GJ, Weiss MS, Hedderich R, Kahnt J, Ermler U, Warkentin E FEBS Lett. 2005 Aug 29;579(21):4600-4. PMID:16098517<ref>PMID:16098517</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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The line below this paragraph, {{ABSTRACT_PUBMED_16098517}}, adds the Publication Abstract to the page
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<div class="pdbe-citations 2a5w" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 16098517 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_16098517}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Archaeoglobus fulgidus DSM 4304]]
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2A5W is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Archaeoglobus_fulgidus_dsm_4304 Archaeoglobus fulgidus dsm 4304]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A5W OCA].
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[[Category: Large Structures]]
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[[Category: Ermler U]]
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==Reference==
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[[Category: Hedderich R]]
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X-ray structure of the gamma-subunit of a dissimilatory sulfite reductase: fixed and flexible C-terminal arms., Mander GJ, Weiss MS, Hedderich R, Kahnt J, Ermler U, Warkentin E, FEBS Lett. 2005 Aug 29;579(21):4600-4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16098517 16098517]
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[[Category: Kahnt J]]
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[[Category: Archaeoglobus fulgidus dsm 4304]]
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[[Category: Mander GJ]]
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[[Category: Single protein]]
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[[Category: Warkentin E]]
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[[Category: Ermler, U.]]
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[[Category: Weiss MS]]
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[[Category: Hedderich, R.]]
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[[Category: Kahnt, J.]]
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[[Category: Mander, G J.]]
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[[Category: Warkentin, E.]]
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[[Category: Weiss, M S.]]
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[[Category: Orthogonal helix bundle]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 03:18:31 2008''
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Current revision

Crystal structure of the oxidized gamma-subunit of the dissimilatory sulfite reductase (DsrC) from Archaeoglobus fulgidus

PDB ID 2a5w

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